Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DA379_RS03785 Genome accession   NZ_CP028441
Coordinates   695595..696251 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain 131-4     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 690595..701251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DA379_RS03760 oppF 691124..692041 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  DA379_RS03765 - 692148..693335 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  DA379_RS03770 - 693453..694031 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  DA379_RS03775 spx 694210..694605 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  DA379_RS03780 - 694663..695319 (-) 657 WP_003155033.1 TerC family protein -
  DA379_RS19695 - 695502..695612 (+) 111 Protein_720 adaptor protein MecA -
  DA379_RS03785 mecA 695595..696251 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  DA379_RS03790 - 696402..697562 (+) 1161 WP_003155030.1 competence protein CoiA family protein -
  DA379_RS03795 pepF 697790..699619 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  DA379_RS19605 - 699657..699824 (-) 168 WP_003155026.1 hypothetical protein -
  DA379_RS03800 spxH 700110..701012 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=285060 DA379_RS03785 WP_003155032.1 695595..696251(+) (mecA) [Bacillus velezensis strain 131-4]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=285060 DA379_RS03785 WP_003155032.1 695595..696251(+) (mecA) [Bacillus velezensis strain 131-4]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment