Detailed information NTG0285003

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DA378_RS11010
• Genome accession: NZ_CP028440
• Coordinates: 2281001..2283436 (-)
• Length: 811 a.a.
• NCBI ID: WP_003156399.1
• Uniprot ID: -
• Organism: Bacillus velezensis strain J7-1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2276001..2288436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DA378_RS10985	ispF	2276048..2276524 (-)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
DA378_RS10990	ispD	2276517..2277215 (-)	699	WP_003156405.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
DA378_RS10995	-	2277228..2278328 (-)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
DA378_RS11000	disA	2278442..2279524 (-)	1083	WP_003156401.1	DNA integrity scanning diadenylate cyclase DisA	-
DA378_RS11005	radA	2279528..2280907 (-)	1380	WP_003156400.1	DNA repair protein RadA	Machinery gene
DA378_RS11010	clpC	2281001..2283436 (-)	2436	WP_003156399.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
DA378_RS11015	-	2283433..2284524 (-)	1092	WP_003156398.1	protein arginine kinase	-
DA378_RS11020	-	2284524..2285081 (-)	558	WP_003156397.1	UvrB/UvrC motif-containing protein	-
DA378_RS11025	ctsR	2285095..2285559 (-)	465	WP_003156396.1	transcriptional regulator CtsR	-

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 90104.53 Da
• Isoelectric Point: 5.8528

>NTDB_id=285003 DA378_RS11010 WP_003156399.1 2281001..2283436(-) (clpC) [Bacillus velezensis strain J7-1]
MMFGRFTERAQKVLALAQEEALRLGHTNIGTEHILLGLVREGEGIAFKALEALGLNSDKMQKEVESLIGRGQESATSVPH
YTPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNETGSSASGANSNAN
TPTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIQVDQPSADESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAG
SKVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEDTKKTWKEKQGQENSEVSVEDIAMV
VSSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESIFGDEEAMIRVDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTILIMTSNVGASELKRNKYVGFNVQDESQNHKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHL
TDIVSLMSDQLTKRLKEQDLSIELTDAAKAKVAEEGVDLEYGARPLRRAIQKHVEDRLSEELLRGNIDKGQHIVLDVEDG
EFVVKTTAKTN

Nucleotide

• Length: 2436 bp

>NTDB_id=285003 DA378_RS11010 WP_003156399.1 2281001..2283436(-) (clpC) [Bacillus velezensis strain J7-1]
ATGATGTTTGGAAGGTTTACAGAGCGAGCTCAAAAGGTATTGGCACTGGCACAGGAGGAAGCACTGCGCTTAGGCCATAC
AAATATCGGAACTGAACATATACTATTAGGGTTAGTCCGTGAAGGTGAAGGGATCGCATTTAAAGCTTTAGAAGCTCTTG
GCCTTAATTCAGATAAAATGCAGAAAGAAGTGGAAAGTTTGATCGGTCGAGGGCAGGAAAGTGCCACCTCTGTTCCTCAT
TACACACCTCGAGCCAAAAAGGTAATAGAGCTATCAATGGATGAAGCCAGAAAGCTAGGACATTCTTATGTGGGAACAGA
ACACATACTTCTCGGATTGATCCGTGAAGGAGAAGGCGTGGCGGCGAGAGTTCTGAATAATCTCGGTGTCAGCTTAAATA
AAGCGAGACAGCAAGTGCTGCAGCTTCTGGGAAGCAATGAGACGGGGTCTTCTGCATCCGGTGCCAACAGCAATGCAAAC
ACGCCGACGCTTGACAGTCTGGCGCGTGATTTAACTGCGATTGCGAAGGAAGACAGTCTTGATCCGGTTATCGGGCGAAG
CAAAGAAATTCAGCGTGTTATTGAGGTATTAAGCCGCAGAACGAAAAATAATCCCGTTCTTATCGGAGAACCGGGTGTAG
GTAAAACTGCGATTGCTGAAGGCCTCGCACAGCAGATCATCAATAATGAAGTGCCGGAAATTTTACGTGATAAACGCGTA
ATGACGTTAGACATGGGTACGGTTGTAGCCGGTACGAAATACCGCGGAGAATTTGAAGACCGCTTGAAAAAAGTAATGGA
TGAAATACGTCAGGCCGGCAATATTATTTTATTCATTGACGAACTGCATACACTGATCGGAGCGGGGGGAGCAGAAGGTG
CGATTGACGCATCGAATATTTTAAAACCTTCACTGGCCCGCGGAGAGCTTCAATGCATCGGTGCCACAACGCTTGATGAA
TACCGTAAATATATCGAAAAAGACGCGGCTCTCGAGCGCCGTTTCCAGCCGATTCAGGTGGATCAGCCGTCAGCCGATGA
AAGCATTCAAATTTTAAAAGGGCTCCGTGACCGCTATGAAGCGCATCACCGCGTATCCATTACCGATGAAGCGATCGAAG
CCGCGGTTAAATTGTCCGACCGTTATATTTCTGACCGCTTCCTTCCGGATAAAGCGATCGATTTAATTGATGAAGCCGGT
TCAAAAGTGCGTCTCCGTTCTTTCACAACGCCTCCAAACTTAAAAGAGCTTGAGCAGAAACTCGATGAAGTTCGCAAGGA
AAAAGACGCTGCCGTTCAGAGCCAGGAGTTTGAAAAAGCGGCTTCCCTTCGTGATACGGAGCAGCGCCTGAGAGAACAGG
TGGAAGACACGAAAAAAACCTGGAAAGAAAAACAAGGCCAGGAGAACTCCGAAGTTTCTGTAGAGGATATCGCGATGGTT
GTATCCAGCTGGACCGGGGTGCCCGTATCTAAAATTGCCCAAACGGAAACAGATAAGCTTCTCAATATGGAAAGCATTCT
GCATTCCCGCGTCATCGGCCAGGATGAAGCCGTTGTAGCCGTGGCAAAGGCTGTCAGACGTGCAAGAGCCGGACTGAAGG
ACCCGAAACGTCCGATTGGTTCATTCATCTTCTTAGGCCCTACAGGCGTTGGGAAGACAGAGCTGGCAAGAGCGCTGGCG
GAATCCATTTTCGGTGATGAGGAAGCGATGATCAGAGTGGATATGTCCGAATACATGGAGAAACACTCGACTTCACGTCT
TGTCGGTTCTCCTCCGGGATATGTCGGCTATGATGAAGGCGGCCAGCTGACAGAAAAAGTGAGAAGAAAACCTTACTCTG
TCGTATTGCTTGATGAAATTGAAAAAGCACACCCTGATGTGTTTAACATTCTCCTGCAAGTGCTTGAAGACGGACGCTTG
ACTGATTCAAAAGGACGCACTGTGGATTTCCGCAACACGATCCTGATTATGACGTCAAACGTCGGGGCGAGCGAGCTGAA
GCGCAACAAATATGTAGGCTTCAATGTCCAGGATGAATCACAAAACCATAAAGACATGAAAGACAAAGTCATGGGAGAGC
TGAAGCGTGCCTTCAGACCTGAGTTTATCAACCGGATTGACGAAATTATCGTCTTCCACTCCCTTGAGAAAAAACATCTT
ACAGACATCGTGTCGCTTATGTCTGATCAGTTAACAAAACGTCTGAAAGAACAAGATCTCTCTATCGAGCTGACGGATGC
TGCCAAAGCAAAAGTAGCAGAAGAGGGCGTCGATTTGGAATACGGCGCACGCCCGTTAAGAAGAGCGATTCAAAAGCATG
TGGAGGACCGGTTATCAGAAGAACTCCTCAGAGGCAATATTGATAAAGGCCAGCACATTGTTCTTGATGTTGAGGACGGC
GAATTTGTCGTAAAAACAACTGCTAAAACGAACTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (206-318)

• AAA lid domain (AAA_lid_9) (344-445)

• AAA domain (Cdc48 subfamily) (AAA_2) (537-709)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (715-794)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-144)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	96.794	100	0.968
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.688	98.767	0.491
clpC	Streptococcus thermophilus LMD-9	46.359	100	0.471
clpC	Streptococcus thermophilus LMG 18311	46.117	100	0.469
clpC	Streptococcus mutans UA159	44.203	100	0.451
clpC	Streptococcus pneumoniae D39	44.895	100	0.45
clpC	Streptococcus pneumoniae TIGR4	44.895	100	0.45
clpC	Streptococcus pneumoniae Rx1	44.895	100	0.45
clpE	Streptococcus mutans UA159	53.313	80.025	0.427
clpC	Lactococcus lactis subsp. cremoris KW2	49.709	84.834	0.422
clpE	Streptococcus pneumoniae TIGR4	52.388	80.025	0.419
clpE	Streptococcus pneumoniae Rx1	52.388	80.025	0.419
clpE	Streptococcus pneumoniae D39	52.388	80.025	0.419
clpE	Streptococcus pneumoniae R6	52.388	80.025	0.419