Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   SK637_RS04425 Genome accession   NZ_CP028415
Coordinates   807716..809518 (+) Length   600 a.a.
NCBI ID   WP_033688729.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 802716..814518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS04400 (SK637_00858) smpB 804505..804972 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  SK637_RS04405 (SK637_00859) tehB 804987..805847 (+) 861 WP_033688726.1 SAM-dependent methyltransferase TehB -
  SK637_RS04410 - 806069..806260 (+) 192 WP_078352506.1 type II toxin-antitoxin system HicA family toxin -
  SK637_RS04415 (SK637_00860) - 806288..806665 (+) 378 WP_033688727.1 type II toxin-antitoxin system HicB family antitoxin -
  SK637_RS04420 (SK637_00861) coiA 806744..807697 (+) 954 WP_033688728.1 competence protein CoiA Machinery gene
  SK637_RS04425 (SK637_00862) pepF 807716..809518 (+) 1803 WP_033688729.1 oligoendopeptidase F Regulator
  SK637_RS04430 (SK637_00863) - 809520..810233 (+) 714 WP_078352505.1 O-methyltransferase -
  SK637_RS04435 (SK637_00864) prsA 810300..811238 (+) 939 WP_000727953.1 peptidylprolyl isomerase PrsA -
  SK637_RS04440 (SK637_00865) ftsW 811399..812622 (+) 1224 WP_000703373.1 cell division peptidoglycan polymerase FtsW -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69905.78 Da        Isoelectric Point: 4.5310

>NTDB_id=284709 SK637_RS04425 WP_033688729.1 807716..809518(+) (pepF) [Streptococcus mitis strain SK637]
MVLQRHEINEKDTWDLSTIYPTDQAWEEALKDLTEQLEKVAQYEGHLLDSADSLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEEQYADFLEAQPKLQVYQHYFDKLLQGKEHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=284709 SK637_RS04425 WP_033688729.1 807716..809518(+) (pepF) [Streptococcus mitis strain SK637]
ATGGTATTACAAAGACATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGAAAGTAGCCCAGTATGAAGGTCATCTCTTGGATAGTGCGGATAGCC
TACTCGAAATTACTGAATTTTCTCTTGAAATGGAACGCCAAATGGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAAGACACACGTGAAGCCAAGTATCAAGAGTACTATGCTAAGGCCATGACACTCTACAGCCAGCTAGACCAAGCTTTTTC
ATTCTATGAACCTGAATTTATGGAAATCAGTGAAGAGCAGTATGCTGACTTTTTAGAAGCTCAGCCAAAATTGCAGGTTT
ATCAACACTATTTTGACAAGCTTTTGCAAGGCAAGGAACACGTTCTTTCACAACGTGAAGAAGAATTATTAGCTGGAGCT
GGGGAAATCTTTGGTTCGGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTCGACGA
TGATGGTAAGGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAATCGTGAGGTGCGTCGTGGTG
CCTATCAAGCACTTTATGCGACTTATGAACAATTCCAACATACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTGCAA
AACTATCGTGCAAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGAAAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTGCATCGTTACCTTGAACTTCGTTCAAAAATCTTGGGAA
TTTCAGACCTCAAGATGTACGATGTCTACACACCACTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAGGCAGAAGATGCCTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTCAGTGAGCGTTGGATTGA
TGTTTACGAAAACCAAGGCAAGCGTTCAGGGGCCTACTCTGGTGGTTCTTACGATACAAATGCCTTTATGCTTCTCAACT
GGCAGGACAATCTAGACAATCTCTTTACTCTTGTCCATGAGACTGGTCACAGTATGCACTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGAGATTATTCTATCTTCTTGGCTGAGATTGCCTCAACGACCAATGAAAATATTTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGATGATGCAACGCGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCGATTCACCAAGCGGATCAAAATGGTGAAGTCTTGACAAGTGATTTC
TTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCACGCATTCCACACTTCTACTATAACTACTATGTATACCAATATTCAACAGGTTTTGCAGCAGCCTCAGCTTTGGCTG
AAAAGATTGTTCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTATCTCAAGGCAGGTAAATCTGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAATGATGCCTTTGCAGTCTTTGAACGTCGTTT
GAATGAGTTTGAAGCCCTTGTTGAAAAATTGGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.114

99.333

0.667

Multiple sequence alignment