Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SM12261_RS07025 Genome accession   NZ_CP028414
Coordinates   1381261..1382493 (-) Length   410 a.a.
NCBI ID   WP_012972566.1    Uniprot ID   A0A387B487
Organism   Streptococcus mitis NCTC 12261     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1376261..1387493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS07000 (SM12261_1352) whiA 1377450..1378361 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  SM12261_RS07005 (SM12261_1353) - 1378358..1379335 (-) 978 WP_001231080.1 YvcK family protein -
  SM12261_RS07010 (SM12261_1354) rapZ 1379332..1380222 (-) 891 WP_000163055.1 RNase adapter RapZ -
  SM12261_RS07015 (SM12261_1355) - 1380274..1380654 (-) 381 WP_001140420.1 RidA family protein -
  SM12261_RS07020 (SM12261_1356) yihA 1380665..1381252 (-) 588 WP_000422605.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SM12261_RS07025 (SM12261_1357) clpX 1381261..1382493 (-) 1233 WP_012972566.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SM12261_RS09500 (SM12261_1358) - 1382530..1382700 (-) 171 WP_000442260.1 hypothetical protein -
  SM12261_RS07035 (SM12261_1359) - 1382700..1383206 (-) 507 WP_000162491.1 dihydrofolate reductase -
  SM12261_RS07040 (SM12261_1360) - 1383338..1383856 (-) 519 WP_000229882.1 Dps family protein -
  SM12261_RS07045 (SM12261_1361) lytC 1384089..1385699 (-) 1611 WP_078228356.1 choline binding-anchored murein hydrolase LytC -
  SM12261_RS07050 (SM12261_1362) tpiA 1385733..1386491 (-) 759 WP_000087891.1 triose-phosphate isomerase -
  SM12261_RS07055 (SM12261_1363) - 1386589..1387266 (-) 678 WP_000221591.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45681.16 Da        Isoelectric Point: 4.4240

>NTDB_id=284650 SM12261_RS07025 WP_012972566.1 1381261..1382493(-) (clpX) [Streptococcus mitis NCTC 12261]
MPTNRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=284650 SM12261_RS07025 WP_012972566.1 1381261..1382493(-) (clpX) [Streptococcus mitis NCTC 12261]
ATGCCTACAAATAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCAGGTAACAACGCCTTTATCTGTAATGAATGTGTGGAGTTAGCCCAGGAAATCATTCGAGAGGAGTTGGCGGAAGAAG
TCTTGGCAGACTTGTCTGAAGTTCCAAAACCAATCGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAACGTGCCTTGGCAGTGGCAGTTTACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAATATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTTCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCGATTGCGGATGCAACAGCTCTTACTGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTATTGCAGGCTGCTGACTTTAACATTGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCTAAGAAGAGCGAGAACGTATCGATCACACGTGACGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTTAAGA
TTATCGAGGGAACAGTTGCCAGCGTACCGCCTCAAGGTGGACGTAAACATCCACAACAAGAGATGATTCAAGTGGATACT
AAAAATATCCTCTTCATCGTGGGTGGTGCCTTTGATGGTATTGAAGAAATCGTCAAACAACGTCTGGGTGAAAAGGTTAT
CGGATTTGGTCAAAACAATAAAGCGATTGATGAAAACAGCTCTTACATGCAAGAAATCATCGCAGAAGATATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGTTTGCCTGTCTTTGCTGCTCTTGAGCAATTGACGGTTGATGACTTGGTTCGT
ATCTTGAAAGAGCCAAGAAATGCCTTGGTTAAACAATATCAAACCTTGCTTTCTTATGATGATGTCGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCCAACAAGGCCATCGAACGTAAAACGGGTGCGCGTGGTCTTCGCTCTATTATCGAGG
AAACCATGCTAGATGTCATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTCCGCATCACTAAAGAAGCTGTCGAT
GGAACGGATAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387B487

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.073

100

0.871
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment