Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EGX93_RS16430 Genome accession   NZ_CP033762
Coordinates   3132414..3133046 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain FDAARGOS_536     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3127414..3138046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX93_RS16405 (EGX93_16390) yheS 3127583..3129496 (+) 1914 WP_000634796.1 ABC transporter ATP-binding protein -
  EGX93_RS16410 (EGX93_16395) yheT 3129496..3130518 (+) 1023 WP_000057387.1 hydrolase -
  EGX93_RS16415 (EGX93_16400) yheU 3130512..3130730 (+) 219 WP_000907085.1 YheU family protein -
  EGX93_RS16420 (EGX93_16405) prkB 3130784..3131653 (+) 870 WP_001274684.1 phosphoribulokinase -
  EGX93_RS16425 (EGX93_16410) yhfA 3131708..3132112 (-) 405 WP_001148908.1 OsmC family protein -
  EGX93_RS16430 (EGX93_16415) crp 3132414..3133046 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EGX93_RS16435 (EGX93_16420) yhfK 3133097..3135187 (+) 2091 WP_024009357.1 YccS/YhfK family putative transporter -
  EGX93_RS16440 (EGX93_16425) argD 3135254..3136474 (-) 1221 WP_000963800.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EGX93_RS16445 (EGX93_16430) pabA 3136560..3137123 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  EGX93_RS16450 (EGX93_16435) fic 3137155..3137757 (-) 603 WP_001280662.1 putative adenosine monophosphate-protein transferase Fic -
  EGX93_RS16455 (EGX93_16440) yhfG 3137747..3137914 (-) 168 WP_000736859.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=284442 EGX93_RS16430 WP_000242755.1 3132414..3133046(+) (crp) [Escherichia coli strain FDAARGOS_536]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=284442 EGX93_RS16430 WP_000242755.1 3132414..3133046(+) (crp) [Escherichia coli strain FDAARGOS_536]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment