Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   CEP77_RS01020 Genome accession   NZ_CP028325
Coordinates   213091..214875 (+) Length   594 a.a.
NCBI ID   WP_108168998.1    Uniprot ID   -
Organism   Helicobacter pylori strain FDAARGOS_298     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 208091..219875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEP77_RS00990 (CEP77_00990) motB 208863..209630 (+) 768 WP_108168995.1 flagellar motor protein MotB -
  CEP77_RS00995 (CEP77_00995) - 209636..210073 (+) 438 WP_001883762.1 hypothetical protein -
  CEP77_RS01000 (CEP77_01000) - 210142..211803 (+) 1662 WP_108168996.1 ABC transporter permease/substrate-binding protein -
  CEP77_RS01005 (CEP77_01005) - 211805..212446 (+) 642 WP_108168997.1 ATP-binding cassette domain-containing protein -
  CEP77_RS01010 (CEP77_01010) - 212458..212637 (-) 180 WP_001912514.1 hypothetical protein -
  CEP77_RS01015 (CEP77_01015) - 212629..213090 (+) 462 WP_000437179.1 hypothetical protein -
  CEP77_RS01020 (CEP77_01020) uvrC 213091..214875 (+) 1785 WP_108168998.1 excinuclease ABC subunit UvrC Machinery gene
  CEP77_RS01025 (CEP77_01025) - 214886..216151 (+) 1266 WP_108168999.1 homoserine dehydrogenase -
  CEP77_RS01030 (CEP77_01030) - 216152..216496 (+) 345 WP_001211718.1 YraN family protein -
  CEP77_RS01035 (CEP77_01035) trxA 216585..216905 (+) 321 WP_000020199.1 thioredoxin -
  CEP77_RS01040 (CEP77_01040) trxB 216911..217846 (+) 936 WP_108169000.1 thioredoxin-disulfide reductase -
  CEP77_RS01045 (CEP77_01045) - 218054..218875 (+) 822 WP_108169001.1 glycosyltransferase family 25 protein -
  CEP77_RS01050 (CEP77_01050) - 219094..219342 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68551.70 Da        Isoelectric Point: 9.5288

>NTDB_id=284123 CEP77_RS01020 WP_108168998.1 213091..214875(+) (uvrC) [Helicobacter pylori strain FDAARGOS_298]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYSKIAKECLEMIENKDKLIKELELKMECLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSTFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRGQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKHLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGNFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=284123 CEP77_RS01020 WP_108168998.1 213091..214875(+) (uvrC) [Helicobacter pylori strain FDAARGOS_298]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAACAGCAGCGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ACCATCGCGCCAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGTGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAAGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAACGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAGCGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAGTGCATGCCTTATAGGGTGGAAATTTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAATGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATCGATGGAGGGAGGGGGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAACACTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGTGTGAAAAAATTATTGGATTATTTTGGGAATTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment