Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   EFD52_RS07560 Genome accession   NZ_CP033606
Coordinates   1548743..1551073 (-) Length   776 a.a.
NCBI ID   WP_003129443.1    Uniprot ID   Q9CF36
Organism   Lactococcus lactis strain IL6288     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1543743..1556073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EFD52_RS07530 (EFD52_07530) - 1544333..1545316 (-) 984 WP_010906073.1 LacI family DNA-binding transcriptional regulator -
  EFD52_RS07535 (EFD52_07535) purB 1545450..1546745 (-) 1296 WP_003129439.1 adenylosuccinate lyase -
  EFD52_RS07540 (EFD52_07540) aroD 1546942..1547622 (-) 681 WP_003129440.1 type I 3-dehydroquinate dehydratase -
  EFD52_RS07550 (EFD52_07550) - 1547885..1548088 (-) 204 WP_010906074.1 DUF2969 domain-containing protein -
  EFD52_RS07555 (EFD52_07555) trxA 1548332..1548646 (-) 315 WP_003129442.1 thioredoxin -
  EFD52_RS07560 (EFD52_07560) mutS/mutS2 1548743..1551073 (-) 2331 WP_003129443.1 endonuclease MutS2 Machinery gene
  EFD52_RS07565 (EFD52_07565) - 1551118..1551678 (-) 561 WP_003129445.1 CvpA family protein -
  EFD52_RS07570 (EFD52_07570) - 1551838..1552803 (-) 966 WP_003129446.1 NAD(P)/FAD-dependent oxidoreductase -
  EFD52_RS07575 (EFD52_07575) ccpA 1552941..1553939 (-) 999 WP_003129447.1 catabolite control protein A Regulator
  EFD52_RS07580 (EFD52_07580) - 1554154..1555242 (+) 1089 WP_010906076.1 Xaa-Pro peptidase family protein -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87296.22 Da        Isoelectric Point: 6.9607

>NTDB_id=283768 EFD52_RS07560 WP_003129443.1 1548743..1551073(-) (mutS/mutS2) [Lactococcus lactis strain IL6288]
MNKKILQILEYDKVKEQFMNALTTAQGQQELKDLKPLTDKEKIQLLFDEVADFRLLTQENGLLNLGKTNDLTEILRRLEL
EASLSGKEFVEIKKVIQLGINIQRFFDEAENVETPSLAITLEKLVDLSALVKKLEIFDNAGSLYDNASLELMHIRASIKS
HQSEIRKIMQEMLTKNLSSLSENVITIRNDRQVLPVKAENKNKIAGVVHDMSASGQTLYIEPNAVVSLNNKLNQKRIEER
QEITRIYRELASQLKPYSFDIRQNAWLIGHIDFVRAKYLYLAANKATLPELTTDKDITLFAARHPLIEAKIVVTNDIKFD
AGLNTIVITGPNTGGKTITLKTVGLLTILAQSGLPILAADGSRIHLFDDIFADIGDEQSIEQSLSTFSSHMTNIVHILAQ
ADENSLVLFDELGAGTDPKEGAALAIAILENLRERNVKTMASTHYPELKAYGVETQRVINASMEFNIDKMQPTYHLQLGV
PGRSNALEISRRLGLPETIISVASQQISDSEHDVNQMIEKLEEKTREVIESSRNIKKIERENQSLHKDLTKVYNQINRER
EFELEKAQKEAQEVVKKASLEAQEILKNLNDKAALKPHEIIAARKELEGLAPTIDFSKNKVLKKAKAQRGLKQGAEVNVT
SYGQRGKLIRLEKDGRWTVQMGSITTRLNEDEFEVIESPEQIQAKTKNVSKKVTSKVKAQLDLRGMRYEEAELELDNYID
QALLANLIQITIVHGIGTGVIREMVQKKLQKHRHIKSYEYAPINAGGSGATIAILK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=283768 EFD52_RS07560 WP_003129443.1 1548743..1551073(-) (mutS/mutS2) [Lactococcus lactis strain IL6288]
ATGAATAAAAAAATTCTCCAAATATTGGAATATGATAAAGTCAAAGAACAGTTTATGAATGCTTTGACGACAGCGCAGGG
TCAACAAGAATTAAAAGATTTAAAACCTTTGACAGATAAGGAAAAAATTCAGCTCCTTTTTGATGAAGTTGCTGATTTTC
GCTTATTGACCCAAGAAAATGGCCTATTAAATTTAGGAAAAACAAATGATTTAACAGAAATACTCAGACGTCTAGAGCTT
GAAGCCAGTCTTTCAGGCAAGGAATTCGTTGAAATAAAAAAAGTGATTCAATTAGGGATTAATATTCAACGCTTTTTTGA
TGAAGCTGAAAATGTTGAAACACCTTCACTAGCTATTACTTTGGAAAAATTGGTTGATTTATCAGCATTAGTCAAAAAAT
TAGAAATTTTTGATAATGCGGGAAGTCTTTATGATAATGCCAGTCTCGAATTGATGCATATCCGTGCTTCAATCAAGAGT
CATCAATCAGAAATTCGGAAAATCATGCAGGAAATGCTGACCAAAAATCTCTCATCTTTGAGTGAAAATGTCATCACTAT
CCGAAATGACCGACAAGTGCTTCCTGTAAAAGCAGAAAACAAAAATAAAATTGCTGGTGTAGTTCATGATATGTCTGCTT
CAGGTCAAACGCTTTATATTGAACCAAATGCGGTTGTTTCATTAAATAATAAACTTAATCAAAAGAGAATTGAAGAACGC
CAAGAAATCACAAGAATTTATCGTGAGCTTGCTAGTCAATTAAAACCTTATAGCTTTGATATAAGACAAAATGCTTGGCT
GATTGGTCATATTGATTTTGTTCGTGCCAAGTATCTTTATTTAGCAGCGAATAAAGCGACACTTCCAGAATTAACAACCG
ATAAAGATATTACCCTTTTTGCAGCTCGCCATCCTTTGATTGAAGCAAAAATAGTTGTGACAAATGATATTAAATTTGAT
GCAGGGCTCAATACGATTGTTATTACCGGTCCAAATACGGGTGGGAAGACCATTACTTTGAAAACAGTTGGTTTGTTGAC
AATATTGGCTCAATCAGGTCTGCCAATTTTAGCCGCTGATGGCAGTCGAATTCATCTTTTTGATGATATTTTTGCCGATA
TCGGTGATGAGCAATCCATTGAGCAAAGTTTATCAACTTTCTCAAGTCATATGACTAATATTGTTCATATTTTAGCTCAA
GCAGATGAAAATAGTTTGGTCTTGTTTGATGAACTTGGGGCAGGAACTGATCCAAAAGAAGGAGCGGCTCTTGCTATTGC
CATACTGGAAAATTTACGTGAACGAAATGTGAAAACCATGGCAAGTACTCATTATCCTGAGTTAAAAGCTTATGGGGTCG
AAACGCAACGAGTAATCAATGCAAGTATGGAATTTAACATTGATAAAATGCAACCCACTTATCATTTGCAACTGGGAGTG
CCTGGGCGTTCAAATGCCTTGGAGATTTCTAGAAGATTAGGTTTGCCAGAAACCATTATTTCAGTAGCCAGTCAACAAAT
TTCTGACAGTGAGCATGATGTCAATCAGATGATTGAAAAGTTGGAAGAAAAAACGCGTGAAGTGATTGAAAGTTCAAGAA
ATATTAAAAAAATTGAACGAGAAAATCAAAGTTTACATAAAGATTTGACGAAAGTCTATAATCAAATTAATCGCGAGCGC
GAGTTTGAATTAGAAAAAGCACAAAAAGAAGCTCAAGAAGTAGTTAAAAAAGCGAGTCTTGAAGCGCAAGAAATTTTGAA
GAATCTCAATGATAAAGCAGCGTTGAAACCACATGAAATTATTGCTGCTAGAAAAGAACTTGAAGGTTTGGCTCCAACCA
TTGATTTTTCTAAAAATAAGGTTTTGAAAAAAGCGAAAGCACAAAGAGGACTTAAGCAAGGGGCTGAAGTTAATGTCACT
TCTTATGGTCAGCGTGGTAAATTGATTCGTTTAGAAAAAGATGGACGTTGGACGGTTCAGATGGGTTCAATCACGACTCG
TTTAAATGAAGATGAATTTGAAGTGATTGAAAGTCCAGAACAAATTCAAGCCAAAACTAAAAATGTCAGCAAGAAGGTGA
CTTCTAAAGTCAAAGCTCAACTTGATTTACGCGGGATGCGTTATGAAGAAGCAGAACTGGAATTGGATAATTATATTGAC
CAAGCTCTACTTGCAAATTTGATTCAAATTACGATTGTTCATGGGATTGGAACGGGTGTTATTCGAGAAATGGTACAGAA
AAAACTTCAAAAACACCGTCATATTAAATCTTATGAATATGCACCAATTAATGCTGGTGGCTCTGGAGCAACGATTGCTA
TTTTGAAGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(701-776)

MutS2 and Smr-associated SH3 domain (MSSS)

(634-672)

MutS domain V (MutS_V)

(326-508)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CF36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

42.621

100

0.432