Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C7M28_RS18045 Genome accession   NZ_CP028215
Coordinates   3468097..3468753 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain SRCM102750     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3463097..3473753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M28_RS18015 (C7M28_03538) oppF 3463560..3464477 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  C7M28_RS18020 (C7M28_03539) yjbB 3464585..3465802 (+) 1218 WP_080478438.1 MFS transporter -
  C7M28_RS18025 (C7M28_03540) yjbC 3465967..3466545 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  C7M28_RS18030 (C7M28_03541) spx 3466726..3467121 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  C7M28_RS18035 (C7M28_03542) yjbE 3467164..3467820 (-) 657 WP_003232944.1 TerC family protein -
  C7M28_RS18040 - 3467990..3468130 (+) 141 WP_119122854.1 hypothetical protein -
  C7M28_RS18045 (C7M28_03543) mecA 3468097..3468753 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  C7M28_RS18050 - 3468748..3468870 (-) 123 WP_003245684.1 hypothetical protein -
  C7M28_RS18055 (C7M28_03544) coiA 3468944..3470065 (+) 1122 WP_003232938.1 competence protein CoiA Machinery gene
  C7M28_RS18060 (C7M28_03545) pepF 3470295..3472124 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  C7M28_RS18065 (C7M28_03546) - 3472162..3472329 (-) 168 WP_003244944.1 hypothetical protein -
  C7M28_RS18070 (C7M28_03548) spxH 3472643..3473542 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=283297 C7M28_RS18045 WP_003245194.1 3468097..3468753(+) (mecA) [Bacillus subtilis strain SRCM102750]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=283297 C7M28_RS18045 WP_003245194.1 3468097..3468753(+) (mecA) [Bacillus subtilis strain SRCM102750]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment