Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EB818_RS03895 Genome accession   NZ_CP033335
Coordinates   743263..743739 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain TSPY208     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 738263..748739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB818_RS03870 (EB818_03880) - 739472..739573 (+) 102 WP_129322668.1 DUF1617 family protein -
  EB818_RS03875 (EB818_03885) - 739769..740977 (+) 1209 WP_129322669.1 glucosaminidase domain-containing protein -
  EB818_RS03880 (EB818_03890) spei 741246..741923 (+) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  EB818_RS03885 (EB818_03895) speh 741949..742659 (+) 711 WP_129322670.1 streptococcal pyrogenic exotoxin SpeH -
  EB818_RS03895 (EB818_03905) mutX 743263..743739 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  EB818_RS03900 (EB818_03910) - 743797..744978 (+) 1182 WP_129322671.1 AI-2E family transporter -
  EB818_RS03905 (EB818_03915) - 744968..746215 (+) 1248 WP_032460151.1 tetratricopeptide repeat protein -
  EB818_RS03910 (EB818_03920) fbp54 746274..747926 (-) 1653 WP_076639624.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=282985 EB818_RS03895 WP_002984880.1 743263..743739(+) (mutX) [Streptococcus pyogenes strain TSPY208]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=282985 EB818_RS03895 WP_002984880.1 743263..743739(+) (mutX) [Streptococcus pyogenes strain TSPY208]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAAGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACTTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment