Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D3W51_RS13750 Genome accession   NZ_CP033250
Coordinates   2846379..2847035 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ECCHD184     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2841379..2852035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D3W51_RS13715 (D3W51_13920) - 2842509..2843249 (+) 741 WP_032187455.1 hypothetical protein -
  D3W51_RS13740 (D3W51_13945) pgsA 2843945..2844493 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D3W51_RS13745 (D3W51_13950) uvrC 2844550..2846382 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D3W51_RS13750 (D3W51_13955) letA 2846379..2847035 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D3W51_RS25490 (D3W51_13960) - 2847177..2847293 (+) 117 WP_001302039.1 hypothetical protein -
  D3W51_RS13760 yecU 2847331..2847507 (+) 177 WP_000590344.1 protein YecU -
  D3W51_RS13765 (D3W51_13965) yecF 2847494..2847718 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  D3W51_RS13770 (D3W51_13970) sdiA 2847786..2848508 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  D3W51_RS13775 (D3W51_13975) tcyN 2848738..2849490 (-) 753 WP_001273015.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D3W51_RS13780 (D3W51_13980) tcyL 2849487..2850155 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  D3W51_RS13785 (D3W51_13985) dcyD 2850170..2851156 (-) 987 WP_032296855.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=282907 D3W51_RS13750 WP_000611328.1 2846379..2847035(-) (letA) [Escherichia coli strain ECCHD184]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=282907 D3W51_RS13750 WP_000611328.1 2846379..2847035(-) (letA) [Escherichia coli strain ECCHD184]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment