Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C7M19_RS16825 Genome accession   NZ_CP028205
Coordinates   3403424..3404080 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SRCM102741     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3398424..3409080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M19_RS16800 (C7M19_03392) oppF 3398953..3399870 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  C7M19_RS16805 (C7M19_03393) - 3399977..3401164 (+) 1188 WP_059367234.1 putative glycoside hydrolase -
  C7M19_RS16810 (C7M19_03394) - 3401282..3401860 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  C7M19_RS16815 (C7M19_03395) spx 3402039..3402434 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  C7M19_RS16820 (C7M19_03396) - 3402492..3403148 (-) 657 WP_007409109.1 TerC family protein -
  C7M19_RS19885 - 3403331..3403441 (+) 111 Protein_3293 adaptor protein MecA -
  C7M19_RS16825 (C7M19_03397) mecA 3403424..3404080 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  C7M19_RS16830 (C7M19_03398) - 3404231..3405391 (+) 1161 WP_099566553.1 competence protein CoiA family protein -
  C7M19_RS16835 (C7M19_03399) pepF 3405619..3407448 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  C7M19_RS19890 (C7M19_03400) - 3407486..3407653 (-) 168 WP_003155026.1 hypothetical protein -
  C7M19_RS16840 (C7M19_03401) spxH 3407939..3408841 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=282599 C7M19_RS16825 WP_003155032.1 3403424..3404080(+) (mecA) [Bacillus velezensis strain SRCM102741]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=282599 C7M19_RS16825 WP_003155032.1 3403424..3404080(+) (mecA) [Bacillus velezensis strain SRCM102741]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment