Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C7M18_RS12970 Genome accession   NZ_CP028204
Coordinates   2580644..2581300 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SRCM102755     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2575644..2586300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M18_RS12945 (C7M18_02603) oppF 2576173..2577090 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  C7M18_RS12950 (C7M18_02604) - 2577197..2578393 (+) 1197 WP_160216807.1 putative glycoside hydrolase -
  C7M18_RS12955 (C7M18_02605) - 2578502..2579080 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  C7M18_RS12960 (C7M18_02606) spx 2579259..2579654 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  C7M18_RS12965 (C7M18_02607) - 2579712..2580368 (-) 657 WP_014417421.1 TerC family protein -
  C7M18_RS12970 (C7M18_02608) mecA 2580644..2581300 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  C7M18_RS12975 (C7M18_02609) - 2581452..2582612 (+) 1161 WP_100261695.1 competence protein CoiA family protein -
  C7M18_RS12980 (C7M18_02610) pepF 2582840..2584669 (+) 1830 WP_154817838.1 oligoendopeptidase F Regulator
  C7M18_RS19800 (C7M18_02611) - 2584707..2584874 (-) 168 WP_003155026.1 hypothetical protein -
  C7M18_RS12985 (C7M18_02612) spxH 2585160..2586062 (-) 903 WP_021494985.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=282507 C7M18_RS12970 WP_003155032.1 2580644..2581300(+) (mecA) [Bacillus velezensis strain SRCM102755]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=282507 C7M18_RS12970 WP_003155032.1 2580644..2581300(+) (mecA) [Bacillus velezensis strain SRCM102755]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment