Detailed information NTG0282190

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C9J86_RS00430
• Genome accession: NZ_CP028190
• Coordinates: 55489..56532 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN018749
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 50489..61532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9J86_RS00400 (C9J86_00400)	-	50910..52166 (-)	1257	WP_001793983.1	aminopeptidase	-
C9J86_RS00405 (C9J86_00405)	-	52169..52369 (-)	201	WP_000180460.1	DUF1128 family protein	-
C9J86_RS00410 (C9J86_00410)	-	52516..52980 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
C9J86_RS00415 (C9J86_00415)	-	52987..53262 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
C9J86_RS00420 (C9J86_00420)	-	53540..54757 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
C9J86_RS00425 (C9J86_00425)	vraR	54870..55499 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
C9J86_RS00430 (C9J86_00430)	vraS	55489..56532 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
C9J86_RS00435 (C9J86_00435)	liaF	56529..57230 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
C9J86_RS00440 (C9J86_00440)	-	57245..57631 (-)	387	WP_001110178.1	hypothetical protein	-
C9J86_RS00445 (C9J86_00445)	map	57848..58606 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
C9J86_RS00460 (C9J86_00460)	-	59362..60348 (+)	987	WP_001014423.1	FUSC family protein	-
C9J86_RS00465 (C9J86_00465)	-	60537..60950 (-)	414	WP_001643743.1	hypothetical protein	-
C9J86_RS00470 (C9J86_00470)	-	60979..61089 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=282190 C9J86_RS00430 WP_001017131.1 55489..56532(-) (vraS) [Staphylococcus aureus strain CFSAN018749]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=282190 C9J86_RS00430 WP_001017131.1 55489..56532(-) (vraS) [Staphylococcus aureus strain CFSAN018749]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1