Detailed information NTG0282169

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C9J90_RS04785
• Genome accession: NZ_CP028189
• Coordinates: 930351..931394 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN018750
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 925351..936394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9J90_RS04755 (C9J90_04740)	-	925773..927029 (-)	1257	WP_001789555.1	aminopeptidase	-
C9J90_RS04760 (C9J90_04745)	-	927032..927232 (-)	201	WP_000180460.1	DUF1128 family protein	-
C9J90_RS04765 (C9J90_04750)	-	927379..927843 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
C9J90_RS04770 (C9J90_04755)	-	927850..928125 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
C9J90_RS04775 (C9J90_04760)	-	928403..929620 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
C9J90_RS04780 (C9J90_04765)	vraR	929732..930361 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
C9J90_RS04785 (C9J90_04770)	vraS	930351..931394 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
C9J90_RS04790 (C9J90_04775)	liaF	931391..932092 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
C9J90_RS04795 (C9J90_04780)	-	932107..932493 (-)	387	WP_001110179.1	hypothetical protein	-
C9J90_RS04800 (C9J90_04785)	map	932710..933468 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
C9J90_RS04805 (C9J90_04790)	-	933880..934866 (+)	987	WP_000999713.1	FUSC family protein	-
C9J90_RS04815 (C9J90_04800)	-	935297..935710 (-)	414	WP_001670387.1	hypothetical protein	-
C9J90_RS04820 (C9J90_04805)	-	935739..935849 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=282169 C9J90_RS04785 WP_001017131.1 930351..931394(-) (vraS) [Staphylococcus aureus strain CFSAN018750]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=282169 C9J90_RS04785 WP_001017131.1 930351..931394(-) (vraS) [Staphylococcus aureus strain CFSAN018750]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1