Detailed information NTG0028203

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAURJH9_RS10530
• Genome accession: NC_009487
• Coordinates: 2071056..2072099 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus subsp. aureus JH9
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2066056..2077099

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAURJH9_RS10500 (SaurJH9_1933)	-	2066477..2067733 (-)	1257	WP_001795108.1	aminopeptidase	-
SAURJH9_RS10505 (SaurJH9_1934)	-	2067736..2067936 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAURJH9_RS10510 (SaurJH9_1935)	-	2068083..2068547 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAURJH9_RS10515 (SaurJH9_1936)	-	2068554..2068829 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAURJH9_RS10520 (SaurJH9_1937)	-	2069107..2070324 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SAURJH9_RS10525 (SaurJH9_1938)	vraR	2070437..2071066 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SAURJH9_RS10530 (SaurJH9_1939)	vraS	2071056..2072099 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAURJH9_RS10535 (SaurJH9_1940)	liaF	2072096..2072797 (-)	702	WP_000149066.1	cell wall-active antibiotics response protein LiaF	-
SAURJH9_RS10540 (SaurJH9_1941)	-	2072812..2073198 (-)	387	WP_001110179.1	hypothetical protein	-
SAURJH9_RS10545 (SaurJH9_1942)	map	2073415..2074173 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAURJH9_RS10550 (SaurJH9_1943)	-	2074645..2075631 (+)	987	WP_000999717.1	FUSC family protein	-
SAURJH9_RS10555 (SaurJH9_1944)	-	2076062..2076475 (-)	414	WP_001557448.1	hypothetical protein	-
SAURJH9_RS10560	-	2076504..2076614 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=28203 SAURJH9_RS10530 WP_001017131.1 2071056..2072099(-) (vraS) [Staphylococcus aureus subsp. aureus JH9]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=28203 SAURJH9_RS10530 WP_001017131.1 2071056..2072099(-) (vraS) [Staphylococcus aureus subsp. aureus JH9]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1