Detailed information NTG0281946

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: C9J78_RS07430
• Genome accession: NZ_CP028165
• Coordinates: 1423917..1424804 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CFSAN064037
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1418917..1429804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9J78_RS07395 (C9J78_07400)	-	1418919..1419011 (+)	93	WP_010956583.1	hypothetical protein	-
C9J78_RS07400 (C9J78_07405)	-	1419119..1419616 (-)	498	WP_001065267.1	glutathione peroxidase	-
C9J78_RS07405 (C9J78_07410)	-	1419626..1419886 (-)	261	WP_078064828.1	hypothetical protein	-
C9J78_RS07415 (C9J78_07420)	-	1420268..1420381 (-)	114	WP_072491147.1	hypothetical protein	-
C9J78_RS07420 (C9J78_07425)	-	1421057..1423057 (-)	2001	WP_000776722.1	ABC transporter permease	-
C9J78_RS07425 (C9J78_07430)	-	1423054..1423809 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
C9J78_RS07430 (C9J78_07435)	braS	1423917..1424804 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
C9J78_RS07435 (C9J78_07440)	braR	1424815..1425480 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
C9J78_RS07440 (C9J78_07445)	-	1425506..1425706 (-)	201	WP_000604725.1	hypothetical protein	-
C9J78_RS07445 (C9J78_07450)	-	1425904..1427328 (+)	1425	WP_000953759.1	alkaline phosphatase	-
C9J78_RS14315 (C9J78_07455)	-	1427388..1427489 (-)	102	WP_000731972.1	SE2200 family small protein	-
C9J78_RS07455 (C9J78_07460)	-	1427611..1428066 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
C9J78_RS07460 (C9J78_07465)	-	1428311..1429072 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=281946 C9J78_RS07430 WP_000143420.1 1423917..1424804(-) (braS) [Staphylococcus aureus strain CFSAN064037]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=281946 C9J78_RS07430 WP_000143420.1 1423917..1424804(-) (braS) [Staphylococcus aureus strain CFSAN064037]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993