Detailed information NTG0281941

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C9J78_RS03700
• Genome accession: NZ_CP028165
• Coordinates: 716959..718002 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN064037
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 711959..723002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9J78_RS03670 (C9J78_03675)	-	712380..713636 (-)	1257	WP_001793428.1	aminopeptidase	-
C9J78_RS03675 (C9J78_03680)	-	713639..713839 (-)	201	WP_000180460.1	DUF1128 family protein	-
C9J78_RS03680 (C9J78_03685)	-	713986..714450 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
C9J78_RS03685 (C9J78_03690)	-	714457..714732 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
C9J78_RS03690 (C9J78_03695)	-	715010..716227 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
C9J78_RS03695 (C9J78_03700)	vraR	716340..716969 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
C9J78_RS03700 (C9J78_03705)	vraS	716959..718002 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
C9J78_RS03705 (C9J78_03710)	liaF	717999..718700 (-)	702	WP_000149070.1	cell wall-active antibiotics response protein LiaF	-
C9J78_RS03710 (C9J78_03715)	-	718715..719101 (-)	387	WP_001110179.1	hypothetical protein	-
C9J78_RS03715 (C9J78_03720)	map	719318..720076 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
C9J78_RS03725 (C9J78_03730)	-	720603..721589 (+)	987	WP_107240649.1	aromatic acid exporter family protein	-
C9J78_RS03730 (C9J78_03735)	-	721778..722191 (-)	414	WP_025174666.1	hypothetical protein	-
C9J78_RS03735 (C9J78_03740)	-	722220..722330 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=281941 C9J78_RS03700 WP_001017131.1 716959..718002(-) (vraS) [Staphylococcus aureus strain CFSAN064037]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=281941 C9J78_RS03700 WP_001017131.1 716959..718002(-) (vraS) [Staphylococcus aureus strain CFSAN064037]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1