Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   C9J78_RS01425 Genome accession   NZ_CP028165
Coordinates   306482..307456 (-) Length   324 a.a.
NCBI ID   WP_000697222.1    Uniprot ID   A0A2S6D0Y6
Organism   Staphylococcus aureus strain CFSAN064037     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 301482..312456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C9J78_RS01385 (C9J78_01385) gcvT 301983..303074 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  C9J78_RS01390 (C9J78_01390) - 303233..303757 (-) 525 WP_001015120.1 shikimate kinase -
  C9J78_RS01395 (C9J78_01395) - 303747..303893 (-) 147 WP_001789879.1 hypothetical protein -
  C9J78_RS01400 (C9J78_01400) comGF 303990..304487 (-) 498 WP_029656266.1 competence type IV pilus minor pilin ComGF Machinery gene
  C9J78_RS01405 (C9J78_01405) comGE 304405..304704 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  C9J78_RS01410 (C9J78_01410) comGD 304691..305137 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  C9J78_RS01415 (C9J78_01415) comGC 305115..305426 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  C9J78_RS01420 (C9J78_01420) comGB 305440..306510 (-) 1071 WP_000776417.1 competence type IV pilus assembly protein ComGB Machinery gene
  C9J78_RS01425 (C9J78_01425) comGA 306482..307456 (-) 975 WP_000697222.1 competence type IV pilus ATPase ComGA Machinery gene
  C9J78_RS01430 (C9J78_01430) - 307508..308131 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  C9J78_RS01435 (C9J78_01435) - 308128..308457 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  C9J78_RS01440 (C9J78_01440) - 308457..309443 (-) 987 WP_000161315.1 ROK family glucokinase -
  C9J78_RS01445 (C9J78_01445) - 309440..309643 (-) 204 WP_000087561.1 YqgQ family protein -
  C9J78_RS01450 (C9J78_01450) - 309624..311087 (-) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  C9J78_RS01455 (C9J78_01455) - 311099..311638 (-) 540 WP_000164552.1 5-formyltetrahydrofolate cyclo-ligase -
  C9J78_RS01460 (C9J78_01460) rpmG 311847..311996 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36874.92 Da        Isoelectric Point: 8.8508

>NTDB_id=281928 C9J78_RS01425 WP_000697222.1 306482..307456(-) (comGA) [Staphylococcus aureus strain CFSAN064037]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSNNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=281928 C9J78_RS01425 WP_000697222.1 306482..307456(-) (comGA) [Staphylococcus aureus strain CFSAN064037]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAAGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCAATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6D0Y6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997

Multiple sequence alignment