Detailed information NTG0281886

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C9J77_RS06990
• Genome accession: NZ_CP028163
• Coordinates: 1343475..1344518 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN064038
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1338475..1349518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9J77_RS06955 (C9J77_06950)	-	1339090..1339200 (+)	111	WP_014937049.1	hypothetical protein	-
C9J77_RS06960 (C9J77_06955)	-	1339229..1339642 (+)	414	WP_025174370.1	hypothetical protein	-
C9J77_RS06965 (C9J77_06960)	-	1339831..1340817 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
C9J77_RS06975 (C9J77_06970)	map	1341401..1342159 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
C9J77_RS06980 (C9J77_06975)	-	1342376..1342762 (+)	387	WP_001110182.1	hypothetical protein	-
C9J77_RS06985 (C9J77_06980)	liaF	1342777..1343478 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
C9J77_RS06990 (C9J77_06985)	vraS	1343475..1344518 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
C9J77_RS06995 (C9J77_06990)	vraR	1344508..1345137 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
C9J77_RS07000 (C9J77_06995)	-	1345250..1346467 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
C9J77_RS07005 (C9J77_07000)	-	1346745..1347020 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
C9J77_RS07010 (C9J77_07005)	-	1347027..1347491 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
C9J77_RS07015 (C9J77_07010)	-	1347638..1347838 (+)	201	WP_000180460.1	DUF1128 family protein	-
C9J77_RS07020 (C9J77_07015)	-	1347841..1349097 (+)	1257	WP_074347694.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=281886 C9J77_RS06990 WP_001017131.1 1343475..1344518(+) (vraS) [Staphylococcus aureus strain CFSAN064038]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=281886 C9J77_RS06990 WP_001017131.1 1343475..1344518(+) (vraS) [Staphylococcus aureus strain CFSAN064038]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1