Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   C9J77_RS06260 Genome accession   NZ_CP028163
Coordinates   1226525..1227241 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CFSAN064038     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1221525..1232241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C9J77_RS06245 (C9J77_06240) - 1222612..1223562 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  C9J77_RS06250 (C9J77_06245) - 1223711..1225195 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  C9J77_RS06255 (C9J77_06250) - 1225192..1226151 (+) 960 WP_001253294.1 carbohydrate kinase -
  C9J77_RS06260 (C9J77_06255) agrA 1226525..1227241 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  C9J77_RS06265 (C9J77_06260) agrC 1227260..1228552 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  C9J77_RS06270 (C9J77_06265) agrD 1228577..1228717 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  C9J77_RS06275 (C9J77_06270) agrB 1228714..1229283 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  C9J77_RS15390 hld 1229573..1229653 (+) 81 WP_000046022.1 delta-hemolysin -
  C9J77_RS06285 (C9J77_06280) - 1230255..1231040 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  C9J77_RS06290 (C9J77_06285) - 1231348..1231974 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=281884 C9J77_RS06260 WP_000688492.1 1226525..1227241(-) (agrA) [Staphylococcus aureus strain CFSAN064038]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=281884 C9J77_RS06260 WP_000688492.1 1226525..1227241(-) (agrA) [Staphylococcus aureus strain CFSAN064038]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment