Detailed information NTG0281880

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: C9J77_RS02990
• Genome accession: NZ_CP028163
• Coordinates: 607409..608296 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain CFSAN064038
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 602409..613296

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9J77_RS02960 (C9J77_02955)	-	603142..603903 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
C9J77_RS02965 (C9J77_02960)	-	604147..604602 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
C9J77_RS15355 (C9J77_02965)	-	604724..604825 (+)	102	WP_000731972.1	SE2200 family small protein	-
C9J77_RS02975 (C9J77_02970)	-	604885..606309 (-)	1425	WP_000953736.1	alkaline phosphatase	-
C9J77_RS02980 (C9J77_02975)	-	606507..606707 (+)	201	WP_000604731.1	hypothetical protein	-
C9J77_RS02985 (C9J77_02980)	braR	606733..607398 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
C9J77_RS02990 (C9J77_02985)	braS	607409..608296 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
C9J77_RS02995 (C9J77_02990)	-	608404..609159 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
C9J77_RS03000 (C9J77_02995)	-	609156..611156 (+)	2001	WP_000776741.1	ABC transporter permease	-
C9J77_RS03005 (C9J77_03000)	-	611825..611938 (+)	114	WP_014937089.1	hypothetical protein	-
C9J77_RS03015 (C9J77_03010)	-	612320..612580 (+)	261	WP_014937088.1	hypothetical protein	-
C9J77_RS03020 (C9J77_03015)	-	612590..613087 (+)	498	WP_001065267.1	glutathione peroxidase	-
C9J77_RS03025 (C9J77_03020)	-	613195..613287 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=281880 C9J77_RS02990 WP_000143420.1 607409..608296(+) (braS) [Staphylococcus aureus strain CFSAN064038]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=281880 C9J77_RS02990 WP_000143420.1 607409..608296(+) (braS) [Staphylococcus aureus strain CFSAN064038]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993