Detailed information NTG0281837

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LL14B4_RS12035
• Genome accession: NZ_CP028160
• Coordinates: 2421974..2423002 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis subsp. lactis strain 14B4
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2416974..2428002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL14B4_RS12010 (LL14B4_12000)	-	2417241..2417963 (-)	723	WP_033900892.1	ABC transporter permease	-
LL14B4_RS12015 (LL14B4_12005)	-	2417965..2418816 (-)	852	WP_033900890.1	ABC transporter ATP-binding protein	-
LL14B4_RS12020 (LL14B4_12010)	-	2418813..2420078 (-)	1266	WP_033900888.1	radical SAM/SPASM domain-containing protein	-
LL14B4_RS12025 (LL14B4_12015)	-	2420075..2420668 (-)	594	WP_033900886.1	hypothetical protein	-
LL14B4_RS13355	-	2420723..2420914 (-)	192	WP_136122481.1	hypothetical protein	-
LL14B4_RS12030 (LL14B4_12020)	-	2420997..2421854 (-)	858	WP_033900885.1	Rgg/GadR/MutR family transcriptional regulator	-
LL14B4_RS12035 (LL14B4_12025)	sepM	2421974..2423002 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
LL14B4_RS12040 (LL14B4_12030)	coaD	2422989..2423486 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LL14B4_RS12045 (LL14B4_12035)	rsmD	2423534..2424073 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LL14B4_RS12050 (LL14B4_12040)	-	2424243..2425463 (-)	1221	WP_003132654.1	MDR family MFS transporter	-
LL14B4_RS12055 (LL14B4_12045)	lmrP	2425546..2426772 (-)	1227	WP_033900880.1	multidrug efflux MFS transporter LmrP	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=281837 LL14B4_RS12035 WP_003132657.1 2421974..2423002(-) (sepM) [Lactococcus lactis subsp. lactis strain 14B4]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=281837 LL14B4_RS12035 WP_003132657.1 2421974..2423002(-) (sepM) [Lactococcus lactis subsp. lactis strain 14B4]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTACCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAGCTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGTAAAACAGGAATAGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491