Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SPCG_RS01010 Genome accession   NC_010582
Coordinates   189081..189521 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae CGSP14     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 184081..194521
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPCG_RS00975 (SPCG_0181) - 184294..184518 (+) 225 Protein_190 hypothetical protein -
  SPCG_RS14005 - 184496..184621 (+) 126 WP_257379697.1 hypothetical protein -
  SPCG_RS00985 (SPCG_0182) - 184713..185282 (-) 570 WP_000748406.1 MptD family putative ECF transporter S component -
  SPCG_RS11860 - 185428..185628 (+) 201 Protein_193 helix-turn-helix domain-containing protein -
  SPCG_RS00990 (SPCG_0183) - 185680..186213 (+) 534 WP_000729029.1 hypothetical protein -
  SPCG_RS00995 (SPCG_0184) nrdI 186291..186761 (+) 471 WP_000849619.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SPCG_RS01000 (SPCG_0185) - 187054..188316 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  SPCG_RS01005 (SPCG_0186) - 188626..189084 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  SPCG_RS01010 (SPCG_0187) brsR 189081..189521 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  SPCG_RS01015 (SPCG_0188) hexB 189877..191826 (+) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPCG_RS01020 (SPCG_0189) ribE 192151..192618 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  SPCG_RS01025 (SPCG_0190) - 192619..193824 (-) 1206 WP_001842537.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  SPCG_RS01030 (SPCG_0191) ribE 193844..194479 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=28172 SPCG_RS01010 WP_000861956.1 189081..189521(-) (brsR) [Streptococcus pneumoniae CGSP14]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=28172 SPCG_RS01010 WP_000861956.1 189081..189521(-) (brsR) [Streptococcus pneumoniae CGSP14]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment