Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   C9I27_RS06860 Genome accession   NZ_CP028148
Coordinates   1318506..1319543 (-) Length   345 a.a.
NCBI ID   WP_002989068.1    Uniprot ID   Q1JKX2
Organism   Streptococcus pyogenes strain TJ11-001     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1313506..1324543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C9I27_RS06835 - 1313510..1314037 (-) 528 WP_002983837.1 Dps family protein -
  C9I27_RS06840 - 1314265..1314891 (+) 627 WP_002989076.1 A24 family peptidase -
  C9I27_RS06845 rlmN 1314973..1316052 (-) 1080 WP_002989074.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  C9I27_RS06850 - 1316056..1316676 (-) 621 WP_032461520.1 YutD family protein -
  C9I27_RS06855 - 1317124..1318101 (-) 978 WP_002989070.1 LacI family DNA-binding transcriptional regulator -
  C9I27_RS06860 sepM 1318506..1319543 (-) 1038 WP_002989068.1 SepM family pheromone-processing serine protease Regulator
  C9I27_RS06865 coaD 1319530..1320021 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  C9I27_RS06870 rsmD 1320011..1320550 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  C9I27_RS06875 asnA 1320673..1321665 (-) 993 WP_002983817.1 aspartate--ammonia ligase -
  C9I27_RS06880 arcC 1321979..1322929 (-) 951 WP_002989065.1 carbamate kinase -
  C9I27_RS06885 - 1322949..1324280 (-) 1332 WP_002989063.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37527.17 Da        Isoelectric Point: 9.5788

>NTDB_id=281700 C9I27_RS06860 WP_002989068.1 1318506..1319543(-) (sepM) [Streptococcus pyogenes strain TJ11-001]
MKRLNKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=281700 C9I27_RS06860 WP_002989068.1 1318506..1319543(-) (sepM) [Streptococcus pyogenes strain TJ11-001]
ATGAAAAGACTTAACAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JKX2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment