Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   At12D1_RS01725 Genome accession   NZ_CP033031
Coordinates   348252..350084 (-) Length   610 a.a.
NCBI ID   WP_080865890.1    Uniprot ID   -
Organism   Agrobacterium tumefaciens strain 12D1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 343252..355084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  At12D1_RS01700 (At12D1_03210) - 343941..344180 (+) 240 WP_003503155.1 DUF4170 domain-containing protein -
  At12D1_RS01705 (At12D1_03220) waaA 344396..345718 (+) 1323 WP_080865886.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  At12D1_RS01710 (At12D1_03230) - 345712..346449 (+) 738 WP_003503151.1 HAD family hydrolase -
  At12D1_RS01715 (At12D1_03240) lpxK 346599..347645 (+) 1047 WP_080865888.1 tetraacyldisaccharide 4'-kinase -
  At12D1_RS01720 (At12D1_03250) - 347879..348100 (-) 222 WP_003503147.1 DUF2093 domain-containing protein -
  At12D1_RS01725 (At12D1_03260) hexB 348252..350084 (-) 1833 WP_080865890.1 DNA mismatch repair endonuclease MutL Machinery gene
  At12D1_RS01730 (At12D1_03270) - 350494..352113 (+) 1620 WP_162692733.1 response regulator -
  At12D1_RS01735 (At12D1_03280) - 352200..353552 (+) 1353 WP_003503140.1 putative bifunctional diguanylate cyclase/phosphodiesterase -
  At12D1_RS01745 (At12D1_03290) - 353737..354624 (-) 888 WP_080865894.1 SMP-30/gluconolactonase/LRE family protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 65616.48 Da        Isoelectric Point: 6.0819

>NTDB_id=281606 At12D1_RS01725 WP_080865890.1 348252..350084(-) (hexB) [Agrobacterium tumefaciens strain 12D1]
MAIKQLSETLINQIAAGEVIERPSSATKELVENAIDAGATRIEIATAGGGKGLVRITDNGSGMSPADLELAVRRHCTSKI
SDTLDDIRTLGFRGEALPSIGSVAKLTITSRQQGAEQGSVISVTGGKVSDVRPAASNAGTIVEVRDLFFATPARLKFLKT
ERAEAAAITEVVKRMAIAFPHIRFVLSGTDRSTLEIPSTGDDHLARMAQILGAEFKDNAIEIDAGREDVTLTGFAGVPTF
NRGNSAHQYVFVNGRPVQDKLLLSAIRGAYAETVPHGRYPVAVLSITLDPAFVDVNVHPAKSDVRFRDPGLIRGLIVGAI
RQALTRDGDRAATTGASQMMNAFRPGYSPSGIRPSPSMAAPAPWSAATSPSRPLAVSGDMQFAEAVQSRFSDITMPTARA
EPREIYETATSPSPEPVLYPLGAARAQLHENYIIAQTENGLVIVDQHAAHERLVFEEMRNALHSRRPPSQVLLIPEIIDL
PEEDCDRLMDHSAGFDALGLVIERFGPGAVAVRETPAMLGEVNVQGLVRQLADEIAEWDAASTLANKLEYVAATMACHGS
VRSGRRMRPEEMNALLRQMENTPGSGQCNHGRPTYIELKLSDIERLFGRS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=281606 At12D1_RS01725 WP_080865890.1 348252..350084(-) (hexB) [Agrobacterium tumefaciens strain 12D1]
ATGGCCATCAAGCAGCTTTCAGAAACCCTTATCAACCAGATCGCCGCCGGCGAGGTCATCGAGAGACCCTCCAGCGCCAC
GAAGGAACTGGTGGAAAACGCCATCGACGCTGGCGCGACCAGGATCGAGATCGCCACGGCGGGCGGCGGCAAGGGGCTGG
TGCGGATTACCGATAACGGTTCCGGCATGTCACCTGCCGACCTGGAGCTTGCGGTCAGGCGTCACTGCACCTCGAAAATT
TCCGATACGCTGGATGATATCCGCACGCTCGGGTTTCGTGGGGAGGCGCTGCCCTCCATCGGCTCTGTCGCCAAGCTGAC
GATTACCAGCCGCCAACAGGGCGCAGAACAGGGTTCGGTGATTTCCGTCACCGGCGGCAAGGTTTCCGATGTCCGGCCCG
CCGCCTCGAATGCCGGTACAATCGTCGAGGTGCGCGACCTGTTTTTCGCCACCCCCGCGCGGCTGAAATTCCTGAAGACG
GAACGGGCCGAGGCGGCCGCGATTACCGAAGTCGTCAAGCGTATGGCGATCGCCTTCCCGCATATCCGTTTCGTGCTATC
AGGCACCGACCGTTCGACGCTCGAAATTCCTTCGACCGGCGACGATCATCTGGCCCGCATGGCGCAGATTCTGGGTGCCG
AGTTCAAGGACAACGCCATCGAGATCGATGCAGGGCGCGAGGATGTGACGCTGACCGGTTTTGCCGGTGTTCCGACCTTC
AATCGCGGCAACTCGGCGCATCAATATGTCTTCGTCAACGGCCGCCCGGTGCAGGACAAGCTGCTTTTATCCGCCATTCG
CGGCGCTTATGCCGAAACCGTGCCGCATGGGCGATATCCGGTCGCGGTGCTGTCCATCACGCTTGACCCCGCCTTTGTGG
ATGTGAACGTGCATCCGGCGAAATCCGACGTGCGTTTTCGCGATCCCGGCCTCATTCGCGGGCTGATCGTCGGCGCGATC
CGTCAGGCGTTGACGCGCGACGGCGATAGGGCCGCGACGACGGGCGCGAGCCAGATGATGAATGCGTTCCGCCCCGGCTA
TAGCCCGTCCGGCATCAGGCCCTCGCCTTCCATGGCAGCCCCCGCGCCGTGGTCCGCCGCCACCTCACCGTCGCGGCCGC
TTGCGGTTTCCGGGGACATGCAATTTGCCGAGGCGGTGCAATCGCGCTTTTCCGACATCACCATGCCGACGGCGCGGGCC
GAGCCTCGGGAGATCTACGAGACCGCCACGAGCCCCTCGCCGGAACCCGTGCTTTACCCGCTCGGCGCTGCGCGGGCGCA
GCTGCACGAGAACTACATCATCGCCCAGACGGAAAACGGCCTTGTCATCGTCGACCAGCATGCCGCGCATGAGCGGCTGG
TGTTTGAGGAAATGCGCAATGCACTGCATTCCCGGCGTCCGCCGTCGCAGGTGCTGCTCATCCCTGAAATCATCGATTTG
CCGGAAGAGGATTGCGACCGGCTGATGGATCACTCCGCCGGGTTCGATGCGCTGGGGCTCGTCATCGAACGTTTCGGGCC
GGGCGCGGTCGCCGTCCGGGAAACGCCTGCCATGCTGGGTGAGGTCAATGTGCAGGGGCTGGTGCGTCAGCTTGCCGACG
AGATCGCCGAATGGGACGCCGCCTCCACGCTTGCCAACAAGCTGGAATATGTCGCGGCCACCATGGCCTGCCACGGCTCG
GTGCGTTCCGGCCGGCGTATGCGGCCGGAAGAGATGAACGCGCTTCTACGGCAGATGGAAAACACGCCGGGTTCCGGTCA
ATGCAATCATGGCCGACCGACCTATATCGAACTGAAACTTTCCGATATAGAACGGCTCTTCGGCCGCAGCTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(24-122)

MutL C terminal dimerisation domain (MutL_C)

(420-566)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

34.003

100

0.361