Detailed information NTG0281600

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: C5P47_RS06190
• Genome accession: NZ_CP028140
• Coordinates: 1206579..1207616 (-)
• Length: 345 a.a.
• NCBI ID: WP_032464469.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS979
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1201579..1212616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C5P47_RS06165 (C5P47_06150)	-	1201583..1202110 (-)	528	WP_002983837.1	Dps family protein	-
C5P47_RS06170 (C5P47_06155)	-	1202338..1202964 (+)	627	WP_002983834.1	A24 family peptidase	-
C5P47_RS06175 (C5P47_06160)	rlmN	1203046..1204125 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
C5P47_RS06180 (C5P47_06165)	-	1204129..1204749 (-)	621	WP_032464468.1	YutD family protein	-
C5P47_RS06185 (C5P47_06170)	-	1205197..1206174 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
C5P47_RS06190 (C5P47_06175)	sepM	1206579..1207616 (-)	1038	WP_032464469.1	SepM family pheromone-processing serine protease	Regulator
C5P47_RS06195 (C5P47_06180)	coaD	1207603..1208094 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
C5P47_RS06200 (C5P47_06185)	rsmD	1208084..1208623 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
C5P47_RS06205 (C5P47_06190)	asnA	1208746..1209738 (-)	993	WP_032464470.1	aspartate--ammonia ligase	-
C5P47_RS06210 (C5P47_06195)	arcC	1210051..1211001 (-)	951	WP_010922501.1	carbamate kinase	-
C5P47_RS06215 (C5P47_06200)	-	1211021..1212352 (-)	1332	WP_032464471.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.17 Da
• Isoelectric Point: 9.5788

>NTDB_id=281600 C5P47_RS06190 WP_032464469.1 1206579..1207616(-) (sepM) [Streptococcus pyogenes strain NGAS979]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGN
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=281600 C5P47_RS06190 WP_032464469.1 1206579..1207616(-) (sepM) [Streptococcus pyogenes strain NGAS979]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAC
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69