Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   COSY_RS03570 Genome accession   NC_009465
Coordinates   743870..744829 (+) Length   319 a.a.
NCBI ID   WP_011930093.1    Uniprot ID   A5CW33
Organism   Candidatus Vesicomyosocius okutanii     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 738870..749829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COSY_RS03550 (COSY_0707) thrC 739597..740661 (+) 1065 WP_011930089.1 threonine synthase -
  COSY_RS03555 (COSY_0708) cysM 740680..741567 (+) 888 WP_011930090.1 cysteine synthase CysM -
  COSY_RS03560 (COSY_0709) - 741564..742847 (+) 1284 WP_011930091.1 chloride channel protein -
  COSY_RS03565 (COSY_0710) - 742834..743256 (-) 423 WP_011930092.1 CopD family protein -
  COSY_RS03570 (COSY_0711) pilA 743870..744829 (+) 960 WP_011930093.1 signal recognition particle-docking protein FtsY Machinery gene
  COSY_RS03575 (COSY_0712) hemC 745572..746486 (-) 915 WP_011930094.1 hydroxymethylbilane synthase -
  COSY_RS03580 (COSY_0713) - 746485..746883 (+) 399 WP_011930095.1 hypothetical protein -
  COSY_RS03585 (COSY_0714) argH 746962..748404 (+) 1443 WP_011930096.1 argininosuccinate lyase -
  COSY_RS03590 (COSY_0715) fmt 748404..749372 (+) 969 WP_011930097.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 35018.35 Da        Isoelectric Point: 10.1492

>NTDB_id=28115 COSY_RS03570 WP_011930093.1 743870..744829(+) (pilA) [Candidatus Vesicomyosocius okutanii]
MFNFLKKNRSKSENLGTNKPTSLKQRLDKSRQKLGYSLSSLLLGKKEINENLLEELETLLITADVGINTTDKIIKSTRKN
ASRKTLKNAESLYQFLKDELAKLFIENNQLNISINETFVILVVGVNGAGKTTLIGKLAKSFQNQGKSVMLAAGDTFRAAA
IEQLKIWGQRNNIPVVAKTLGADTASVIFDAYQSAQAKNIDILLADTAGRLHTQDNLMQELAKIKRVITKQNINAPHETM
LVIDGGSGQNIINQAKEFNKAVNLSGISITKLDGTAKGGGLFSIADELNLPIRYIGIGEGIDDLKIFQPKEFINALFDQ

Nucleotide


Download         Length: 960 bp        

>NTDB_id=28115 COSY_RS03570 WP_011930093.1 743870..744829(+) (pilA) [Candidatus Vesicomyosocius okutanii]
ATGTTTAATTTTTTAAAAAAAAATCGGTCAAAATCAGAAAATTTAGGCACAAACAAACCAACTTCATTAAAGCAACGCCT
AGATAAATCTAGACAAAAATTAGGATATAGCTTATCTTCTTTATTGTTGGGCAAAAAAGAAATTAATGAGAATTTATTAG
AAGAACTAGAAACACTATTAATTACTGCTGATGTCGGTATTAATACCACAGATAAAATAATAAAATCTACACGTAAAAAT
GCTTCTAGAAAAACCTTAAAAAATGCTGAAAGCTTGTATCAATTTTTAAAAGATGAATTGGCTAAACTATTCATTGAAAA
CAACCAACTTAATATTAGTATTAATGAAACTTTTGTTATTCTAGTCGTAGGTGTTAATGGCGCTGGTAAAACTACCTTGA
TTGGTAAATTAGCAAAATCTTTTCAAAATCAAGGCAAATCGGTTATGCTAGCAGCAGGCGATACTTTCCGCGCTGCAGCC
ATTGAACAACTAAAAATATGGGGACAACGCAATAATATCCCTGTTGTAGCAAAAACTTTAGGTGCTGATACTGCTTCTGT
CATTTTTGATGCCTACCAATCAGCACAAGCCAAGAATATTGATATCCTGCTTGCTGATACTGCGGGGCGATTACATACAC
AAGACAATCTTATGCAAGAATTAGCTAAAATTAAACGCGTTATTACCAAACAAAATATAAATGCGCCACATGAAACTATG
CTAGTTATTGACGGAGGATCAGGACAAAATATCATCAATCAAGCTAAAGAGTTTAATAAGGCAGTTAATCTAAGTGGTAT
TAGTATAACTAAACTAGATGGTACTGCTAAAGGCGGAGGGTTGTTTTCGATTGCTGACGAACTCAATTTACCTATTCGCT
ATATTGGCATAGGTGAAGGGATTGATGATCTTAAAATTTTTCAACCTAAAGAATTCATAAACGCTTTGTTTGATCAATAA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(118-317)

SRP54-type protein, helical bundle domain (SRP54_N)

(35-100)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A5CW33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

53.356

93.417

0.498

Multiple sequence alignment