Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   D4I62_RS03575 Genome accession   NZ_CP032907
Coordinates   741281..742516 (-) Length   411 a.a.
NCBI ID   WP_139533365.1    Uniprot ID   -
Organism   Helicobacter pylori strain 24-A-EK1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 736281..747516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4I62_RS08150 - 738196..738390 (-) 195 WP_232262232.1 hypothetical protein -
  D4I62_RS03555 - 738455..738928 (-) 474 WP_139533364.1 hypothetical protein -
  D4I62_RS03560 - 738925..739416 (-) 492 Protein_685 ATPase, T2SS/T4P/T4SS family -
  D4I62_RS03565 tnpA 739586..740053 (+) 468 WP_139533177.1 IS200/IS605 family transposase -
  D4I62_RS03570 - 740022..741170 (+) 1149 WP_139533176.1 RNA-guided endonuclease TnpB family protein -
  D4I62_RS03575 comB10 741281..742516 (-) 1236 WP_139533365.1 DNA type IV secretion system protein ComB10 Machinery gene
  D4I62_RS03580 - 742513..744054 (-) 1542 WP_139533366.1 TrbG/VirB9 family P-type conjugative transfer protein -
  D4I62_RS03585 - 744054..745223 (-) 1170 WP_139533367.1 VirB8/TrbF family protein -
  D4I62_RS03590 - 745340..747373 (-) 2034 WP_139533368.1 type IA DNA topoisomerase -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 46489.62 Da        Isoelectric Point: 10.0077

>NTDB_id=280869 D4I62_RS03575 WP_139533365.1 741281..742516(-) (comB10) [Helicobacter pylori strain 24-A-EK1]
MKKLLLLLEHKIIKIGLIIVIVLAGFFLFYEQEIKEKAVNVSQGKFPTSSYLFQAYEGIKNKIDTINEVKPNDETKSVNE
NIEKTQKDLDDFNALVQKLPNLPKDFNKTLIKPQSPSFNYNTANEEEKIRLVILASRISSQKETQPPISIKNSVSHTKSK
EKQELEKEYGSSGFKNFKRKNVASSENKLLRTITADRMIPAILITPISSEIGGSKIVAQVESDIYATMGRAVLIPKGSRA
IGYYNSNNKIGEYRLEIAWNRIITPQGVNIILSDAKGADVKGYNGMIGTLHNKYWERYGIPLSLSTLSNGLLIGLTSGLT
EAMKNKRGGFNQNYFGDYMMMQMTRQTGISLNNIIAQIMRDQIRIKPIITIREGSHIFISPNTDIWFPIPKNNEILAKFF
NEEKEQNNDTK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=280869 D4I62_RS03575 WP_139533365.1 741281..742516(-) (comB10) [Helicobacter pylori strain 24-A-EK1]
ATGAAAAAACTTCTTTTACTTTTAGAGCATAAAATCATAAAAATTGGCTTAATTATTGTGATTGTATTAGCTGGTTTTTT
TCTTTTTTACGAACAAGAAATCAAAGAAAAAGCTGTTAATGTTTCTCAAGGTAAATTCCCTACTTCATCTTATTTGTTTC
AAGCTTACGAAGGCATTAAGAATAAAATAGATACTATCAATGAAGTGAAACCAAACGATGAAACTAAAAGCGTTAATGAG
AATATAGAAAAAACACAAAAAGATTTAGATGATTTTAATGCGCTAGTGCAAAAATTACCAAATTTGCCTAAGGATTTTAA
TAAAACGCTTATTAAACCACAAAGTCCATCCTTCAACTACAATACCGCTAACGAAGAAGAAAAAATCCGCCTTGTGATTT
TAGCGTCTCGTATTAGCAGCCAAAAAGAAACGCAGCCTCCAATCTCTATAAAAAATAGTGTTTCTCACACAAAATCCAAA
GAAAAACAAGAGCTTGAAAAAGAATACGGCTCTAGCGGTTTTAAAAATTTTAAAAGAAAAAATGTAGCGAGCAGTGAAAA
CAAACTTTTGAGAACGATTACAGCTGACAGAATGATCCCAGCCATTCTGATCACTCCTATTAGTAGTGAAATAGGGGGAA
GTAAGATAGTCGCTCAAGTGGAGAGTGATATATACGCAACGATGGGTAGAGCGGTTTTAATCCCTAAAGGGAGTAGAGCC
ATAGGTTATTACAACTCTAATAACAAAATAGGAGAATACCGCTTAGAAATTGCTTGGAATAGGATAATCACGCCACAAGG
GGTCAATATCATACTAAGCGATGCTAAAGGGGCTGATGTCAAGGGCTATAACGGCATGATAGGCACACTCCATAACAAAT
ATTGGGAACGCTATGGTATTCCTTTATCCTTAAGCACCTTGTCAAATGGGCTACTCATAGGCCTTACTAGCGGTCTTACC
GAAGCGATGAAAAACAAAAGGGGTGGTTTTAATCAAAACTATTTTGGAGATTACATGATGATGCAAATGACGAGACAAAC
GGGTATCAGCCTAAATAACATTATCGCTCAAATCATGCGAGATCAAATCAGGATTAAGCCCATTATCACTATTAGAGAAG
GAAGCCATATTTTTATCAGTCCTAATACGGATATTTGGTTCCCTATCCCTAAAAACAATGAAATCTTAGCGAAATTTTTT
AATGAAGAAAAGGAGCAAAACAATGATACAAAATAG

Domains

Predicted by InterProScan.

Bacterial conjugation TrbI-like protein (TrbI)

(192-387)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

54.483

70.56

0.384

Multiple sequence alignment