Detailed information NTG0280697

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: C7M55_RS10680
• Genome accession: NZ_CP027788
• Coordinates: 2051681..2052724 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CMRSA-6
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2046681..2057724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M55_RS10650 (C7M55_10650)	-	2047099..2048355 (-)	1257	WP_001795438.1	aminopeptidase	-
C7M55_RS10655 (C7M55_10655)	-	2048358..2048558 (-)	201	WP_000180461.1	DUF1128 family protein	-
C7M55_RS10660 (C7M55_10660)	-	2048705..2049169 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
C7M55_RS10665 (C7M55_10665)	-	2049176..2049451 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
C7M55_RS10670 (C7M55_10670)	-	2049729..2050946 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
C7M55_RS10675 (C7M55_10675)	vraR	2051062..2051691 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
C7M55_RS10680 (C7M55_10680)	vraS	2051681..2052724 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
C7M55_RS10685 (C7M55_10685)	liaF	2052721..2053422 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
C7M55_RS10690 (C7M55_10690)	-	2053437..2053823 (-)	387	WP_001110179.1	hypothetical protein	-
C7M55_RS10695 (C7M55_10695)	map	2054040..2054798 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
C7M55_RS10705 (C7M55_10705)	-	2055385..2056371 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
C7M55_RS10715 (C7M55_10715)	-	2056802..2057215 (-)	414	WP_001549145.1	hypothetical protein	-
C7M55_RS10720 (C7M55_10720)	-	2057244..2057354 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=280697 C7M55_RS10680 WP_001017131.1 2051681..2052724(-) (vraS) [Staphylococcus aureus strain CMRSA-6]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=280697 C7M55_RS10680 WP_001017131.1 2051681..2052724(-) (vraS) [Staphylococcus aureus strain CMRSA-6]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1