Detailed information NTG0280437

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: C7K40_RS01475
• Genome accession: NZ_CP027771
• Coordinates: 270290..271360 (+)
• Length: 356 a.a.
• NCBI ID: WP_002992231.1
• Uniprot ID: A0A5S4TWS5
• Organism: Streptococcus pyogenes strain DMG1800716
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 265290..276360

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7K40_RS01460 (C7K40_01460)	amiA	265818..267788 (+)	1971	WP_023612875.1	peptide ABC transporter substrate-binding protein	Regulator
C7K40_RS01465 (C7K40_01465)	amiC	267853..269355 (+)	1503	WP_002991105.1	ABC transporter permease	Regulator
C7K40_RS01470 (C7K40_01470)	amiD	269355..270281 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
C7K40_RS01475 (C7K40_01475)	amiE	270290..271360 (+)	1071	WP_002992231.1	ABC transporter ATP-binding protein	Regulator
C7K40_RS01480 (C7K40_01480)	amiF	271353..272276 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
C7K40_RS09795 (C7K40_01485)	-	272314..272403 (-)	90	WP_077707078.1	IS3 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39680.74 Da
• Isoelectric Point: 5.4774

>NTDB_id=280437 C7K40_RS01475 WP_002992231.1 270290..271360(+) (amiE) [Streptococcus pyogenes strain DMG1800716]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=280437 C7K40_RS01475 WP_002992231.1 270290..271360(+) (amiE) [Streptococcus pyogenes strain DMG1800716]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCTTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: A0A5S4TWS5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.667	100	0.775
amiE	Streptococcus thermophilus LMG 18311	75.556	100	0.764
amiE	Streptococcus thermophilus LMD-9	75.556	100	0.764
oppD	Streptococcus mutans UA159	56.677	94.663	0.537