Detailed information
Bioinformatically predicted
Overview
| Name | sxy/tfoX | Type | Regulator |
| Locus tag | C7M85_RS12310 | Genome accession | NZ_CP027766 |
| Coordinates | 2166535..2167164 (-) | Length | 209 a.a. |
| NCBI ID | WP_000839153.1 | Uniprot ID | A0A9Q6Y251 |
| Organism | Escherichia coli strain 2013C-3342 | ||
| Function | positive regulator of competence gene (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2145964..2183374 | 2166535..2167164 | within | 0 |
Gene organization within MGE regions
Location: 2145964..2183374
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C7M85_RS12160 | - | 2146026..2146289 (-) | 264 | WP_000224233.1 | hypothetical protein | - |
| C7M85_RS12165 | - | 2146291..2146508 (-) | 218 | Protein_2247 | DUF4014 family protein | - |
| C7M85_RS12170 | - | 2146541..2146753 (-) | 213 | WP_000935420.1 | hypothetical protein | - |
| C7M85_RS12175 | - | 2146804..2147160 (-) | 357 | WP_000403777.1 | hypothetical protein | - |
| C7M85_RS12180 | - | 2147138..2147599 (-) | 462 | WP_001209480.1 | sigma-E factor regulatory protein RseB domain-containing protein | - |
| C7M85_RS12185 | - | 2147596..2147892 (-) | 297 | WP_001266134.1 | DUF4406 domain-containing protein | - |
| C7M85_RS12190 | - | 2147889..2148311 (-) | 423 | WP_106884040.1 | DUF977 family protein | - |
| C7M85_RS12195 | - | 2148352..2149410 (-) | 1059 | WP_106884039.1 | phage replisome organizer | - |
| C7M85_RS12200 | - | 2149482..2149907 (-) | 426 | WP_106910289.1 | toxin YdaT family protein | - |
| C7M85_RS12205 | - | 2149904..2150119 (-) | 216 | WP_000471549.1 | Cro/CI family transcriptional regulator | - |
| C7M85_RS12210 | - | 2150169..2150885 (+) | 717 | WP_000103686.1 | S24 family peptidase | - |
| C7M85_RS12220 | ydfA | 2151158..2151310 (+) | 153 | WP_000379580.1 | DUF1391 family protein | - |
| C7M85_RS12225 | - | 2151322..2151696 (+) | 375 | WP_000394557.1 | hypothetical protein | - |
| C7M85_RS12230 | dicB | 2152229..2152417 (+) | 189 | WP_000449192.1 | cell division inhibition protein DicB | - |
| C7M85_RS12235 | - | 2152414..2152605 (+) | 192 | WP_001090200.1 | DUF1482 family protein | - |
| C7M85_RS12240 | - | 2152698..2155169 (+) | 2472 | WP_044806223.1 | exonuclease | - |
| C7M85_RS12245 | - | 2155237..2155479 (+) | 243 | WP_000273151.1 | DUF4224 domain-containing protein | - |
| C7M85_RS12250 | - | 2155457..2156476 (+) | 1020 | WP_001299701.1 | tyrosine-type recombinase/integrase | - |
| C7M85_RS12255 | yccA | 2156884..2157543 (+) | 660 | WP_000375138.1 | FtsH protease modulator YccA | - |
| C7M85_RS12260 | tusE | 2157634..2157963 (+) | 330 | WP_000904442.1 | sulfurtransferase TusE | - |
| C7M85_RS12265 | yccX | 2157960..2158238 (-) | 279 | WP_000048244.1 | acylphosphatase | - |
| C7M85_RS12270 | rlmI | 2158333..2159523 (+) | 1191 | WP_106884037.1 | 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI | - |
| C7M85_RS12275 | hspQ | 2159581..2159898 (+) | 318 | WP_001295356.1 | heat shock protein HspQ | - |
| C7M85_RS12280 | yccU | 2159943..2160356 (-) | 414 | WP_000665217.1 | CoA-binding protein | - |
| C7M85_RS12285 | yccT | 2160529..2161191 (+) | 663 | WP_000847791.1 | DUF2057 family protein | - |
| C7M85_RS12290 | mgsA | 2161287..2161745 (+) | 459 | WP_000424181.1 | methylglyoxal synthase | - |
| C7M85_RS12295 | helD | 2161777..2163831 (-) | 2055 | WP_106910290.1 | DNA helicase IV | - |
| C7M85_RS12300 | yccF | 2163954..2164400 (+) | 447 | WP_001261235.1 | YccF domain-containing protein | - |
| C7M85_RS12305 | yccS | 2164410..2166572 (+) | 2163 | WP_000875023.1 | YccS family putative transporter | - |
| C7M85_RS12310 | sxy/tfoX | 2166535..2167164 (-) | 630 | WP_000839153.1 | CRP-S regulon transcriptional coactivator Sxy | Regulator |
| C7M85_RS12315 | sulA | 2167383..2167892 (+) | 510 | WP_000288710.1 | SOS-induced cell division inhibitor SulA | - |
| C7M85_RS12325 | ompA | 2168249..2169289 (+) | 1041 | WP_001400178.1 | porin OmpA | - |
| C7M85_RS12330 | matP | 2169365..2169817 (-) | 453 | WP_000877161.1 | macrodomain Ter protein MatP | - |
| C7M85_RS12335 | ycbZ | 2170003..2171763 (+) | 1761 | WP_000156528.1 | Lon protease family protein | - |
| C7M85_RS12340 | fabA | 2171832..2172350 (+) | 519 | WP_000227927.1 | bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase | - |
| C7M85_RS12345 | rmf | 2172420..2172587 (-) | 168 | WP_000828648.1 | ribosome modulation factor | - |
| C7M85_RS12350 | pqiC | 2172843..2173406 (-) | 564 | WP_000759123.1 | membrane integrity-associated transporter subunit PqiC | - |
| C7M85_RS12355 | pqiB | 2173403..2175043 (-) | 1641 | WP_000445533.1 | intermembrane transport protein PqiB | - |
| C7M85_RS12360 | pqiA | 2175048..2176301 (-) | 1254 | WP_000333176.1 | membrane integrity-associated transporter subunit PqiA | - |
| C7M85_RS12365 | uup | 2176431..2178338 (-) | 1908 | WP_044806219.1 | ABC transporter ATP-binding protein | - |
| C7M85_RS12370 | rlmKL | 2178350..2180458 (-) | 2109 | WP_001086519.1 | bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL | - |
| C7M85_RS12375 | ycbX | 2180702..2181811 (+) | 1110 | WP_000224312.1 | 6-N-hydroxylaminopurine resistance protein YcbX | - |
| C7M85_RS12380 | zapC | 2181808..2182350 (-) | 543 | WP_001295353.1 | cell division protein ZapC | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 24147.02 Da Isoelectric Point: 9.2180
>NTDB_id=280337 C7M85_RS12310 WP_000839153.1 2166535..2167164(-) (sxy/tfoX) [Escherichia coli strain 2013C-3342]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
Nucleotide
Download Length: 630 bp
>NTDB_id=280337 C7M85_RS12310 WP_000839153.1 2166535..2167164(-) (sxy/tfoX) [Escherichia coli strain 2013C-3342]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sxy/tfoX | Escherichia coli BW25113 strain K-12 |
100 |
100 |
1 |