Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   D9C17_RS19660 Genome accession   NZ_CP032863
Coordinates   3645441..3646790 (-) Length   449 a.a.
NCBI ID   WP_033881739.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis strain N2-2     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 3640441..3651790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9C17_RS19645 (D9C17_19645) mhqA 3640641..3641591 (+) 951 WP_014479571.1 ring-cleaving dioxygenase -
  D9C17_RS23160 - 3641700..3641795 (+) 96 Protein_3784 hypothetical protein -
  D9C17_RS19650 (D9C17_19650) ykcB 3641808..3643958 (+) 2151 WP_014479572.1 glycosyltransferase family 39 protein -
  D9C17_RS19655 (D9C17_19655) gtcC 3643970..3644941 (+) 972 WP_014479573.1 glycosyltransferase family 2 protein -
  D9C17_RS19660 (D9C17_19660) htrA 3645441..3646790 (-) 1350 WP_033881739.1 serine protease HtrA Regulator
  D9C17_RS19665 (D9C17_19665) proG 3646959..3647777 (+) 819 WP_014479575.1 pyrroline-5-carboxylate reductase ProG -
  D9C17_RS19670 (D9C17_19670) dppA 3647907..3648731 (+) 825 WP_014479576.1 D-aminopeptidase DppA -
  D9C17_RS19675 (D9C17_19675) dppB 3648748..3649674 (+) 927 WP_003245446.1 dipeptide ABC transporter permease DppB -
  D9C17_RS19680 (D9C17_19680) dppC 3649680..3650642 (+) 963 WP_014479577.1 dipeptide ABC transporter permease DppC -
  D9C17_RS19685 (D9C17_19685) dppD 3650647..3651654 (+) 1008 WP_014479578.1 dipeptide ABC transporter ATP-binding subunit DppD -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 47728.87 Da        Isoelectric Point: 4.6021

>NTDB_id=279834 D9C17_RS19660 WP_033881739.1 3645441..3646790(-) (htrA) [Bacillus subtilis subsp. subtilis strain N2-2]
MDNYRDENRTKGNENEVFLTKENDQSASYSARNVIHDQEKKKRGFGWFRPLLGGVIGGSLALGIYTFTPLGDHDSQDTAK
QSSSQQQTQSVTATSTSSESKKSSSSSSAFKSEDSSKISDMVEDLSPAIVGITNLQAQSNSSLFGSSSSDSSEDTESGSG
SGVIFKKENGKAYIITNNHVVEGASSLKVSLYDGTEVTAKLVGSDSLTDLAVLQISDDHVTKVANFGDSSDLRTGETVIA
IGDPLGKDLSRTVTQGIVSGVDRTVSMSTSAGETSINVIQTDAAINPGNSGGPLLNTDGKIVGINSMKISEDDVEGIGFA
IPSNDVKPIAEELLSKGQIERPYIGVSMLDLEQVPQNYQEGTLGLFGSQLNKGVYIREVASGSPAEKAGLKAEDIIIGLK
GKEIDTGSELRNILYKDAKIGETVEVKILRNGKEMTKKIKLDQKEEKTS

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=279834 D9C17_RS19660 WP_033881739.1 3645441..3646790(-) (htrA) [Bacillus subtilis subsp. subtilis strain N2-2]
ATGGATAACTATCGTGATGAAAACAGAACGAAAGGTAATGAGAATGAGGTCTTTTTAACGAAAGAGAACGATCAGAGCGC
CTCCTACTCGGCCCGCAATGTCATTCATGATCAGGAGAAGAAAAAACGAGGATTCGGATGGTTCAGACCGTTGCTTGGCG
GAGTGATCGGCGGCAGTCTCGCCCTTGGCATTTACACGTTTACACCGCTTGGCGACCATGATTCTCAGGACACTGCAAAA
CAATCATCCAGCCAGCAGCAAACGCAATCTGTTACAGCAACAAGCACCTCCTCTGAATCTAAAAAAAGCTCAAGCAGCTC
ATCTGCATTCAAGAGCGAGGACTCTTCTAAAATCTCAGATATGGTAGAAGACCTTTCACCAGCGATTGTCGGTATTACAA
ATCTTCAGGCACAATCAAACAGCTCTTTGTTCGGCTCTAGTTCTTCTGATTCCAGCGAAGATACAGAAAGCGGTTCAGGG
TCAGGTGTCATTTTCAAAAAAGAGAATGGCAAGGCTTATATCATTACAAATAACCACGTCGTAGAAGGGGCATCATCACT
GAAGGTATCTTTATATGACGGCACTGAGGTTACTGCAAAGCTGGTAGGCAGTGACTCGTTAACTGATTTAGCCGTCCTCC
AAATCAGTGATGACCACGTCACAAAAGTGGCAAACTTCGGTGATTCATCTGATCTTAGAACAGGCGAGACCGTTATTGCG
ATTGGGGATCCGCTTGGAAAAGACCTGTCCCGCACAGTAACACAAGGAATTGTAAGCGGCGTGGACAGAACGGTTTCAAT
GTCTACATCAGCCGGCGAAACGAGCATTAACGTCATTCAGACAGACGCAGCAATTAATCCAGGTAACAGCGGCGGTCCTT
TGTTAAATACAGACGGCAAAATTGTCGGCATTAACAGTATGAAAATCAGTGAGGATGATGTTGAGGGCATCGGATTTGCC
ATTCCAAGCAATGACGTAAAACCGATTGCTGAAGAACTGCTGTCTAAAGGCCAAATTGAACGTCCATATATCGGTGTCAG
CATGCTTGATCTGGAACAAGTGCCGCAAAATTACCAAGAAGGCACACTCGGCCTGTTCGGCAGCCAGCTGAATAAAGGTG
TTTACATCCGTGAGGTCGCTTCAGGCTCTCCTGCTGAAAAGGCCGGATTAAAAGCGGAGGATATTATCATCGGCCTAAAA
GGTAAAGAAATTGATACAGGCAGTGAATTGCGCAATATCTTATATAAAGACGCAAAGATCGGTGAAACCGTTGAAGTGAA
AATTCTCCGAAACGGCAAAGAAATGACGAAAAAAATTAAACTTGATCAAAAAGAAGAGAAAACTTCGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(160-304)

PDZ domain (PDZ_2)

(342-441)

Peptidase family M50 (Peptidase_M50)

(366-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae Rx1

40.796

89.532

0.365
  htrA Streptococcus pneumoniae D39

40.796

89.532

0.365
  htrA Streptococcus pneumoniae R6

40.796

89.532

0.365
  htrA Streptococcus pneumoniae TIGR4

40.796

89.532

0.365
  htrA Streptococcus mitis NCTC 12261

39.32

91.759

0.361

Multiple sequence alignment