Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   SPYM_RS09945 Genome accession   NC_009332
Coordinates   53932..54030 (+) Length   32 a.a.
NCBI ID   WP_020833188.1    Uniprot ID   -
Organism   Streptococcus pyogenes str. Manfredo     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 48932..59030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS00305 (SpyM50031) purK 48994..50067 (+) 1074 WP_011888523.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SPYM_RS00310 (SpyM50032) - 50069..51487 (+) 1419 WP_011888524.1 hypothetical protein -
  SPYM_RS00315 (SpyM50033) purB 51507..52799 (+) 1293 WP_011888525.1 adenylosuccinate lyase -
  SPYM_RS00320 (SpyM50034) comR 52930..53841 (+) 912 WP_011888526.1 helix-turn-helix domain-containing protein Regulator
  SPYM_RS09945 comS 53932..54030 (+) 99 WP_020833188.1 quorum-sensing system DWW-type pheromone Regulator
  SPYM_RS00325 (SpyM50035) ruvB 54061..55059 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  SPYM_RS00330 (SpyM50036) - 55197..55634 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  SPYM_RS00335 (SpyM50037) - 55657..56058 (+) 402 WP_011017240.1 MORN repeat-containing protein -
  SPYM_RS00340 (SpyM50038) - 56055..57830 (+) 1776 WP_011888527.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3758.63 Da        Isoelectric Point: 10.7919

>NTDB_id=27885 SPYM_RS09945 WP_020833188.1 53932..54030(+) (comS) [Streptococcus pyogenes str. Manfredo]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=27885 SPYM_RS09945 WP_020833188.1 53932..54030(+) (comS) [Streptococcus pyogenes str. Manfredo]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

100

100

1

  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437


Multiple sequence alignment