Detailed information NTG0277740

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: D8S77_RS05805
• Genome accession: NZ_CP032700
• Coordinates: 1124732..1126831 (+)
• Length: 699 a.a.
• NCBI ID: WP_129321975.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY556
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1119732..1131831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8S77_RS05780 (D8S77_05785)	deoD	1119751..1120464 (-)	714	WP_129321969.1	purine-nucleoside phosphorylase	-
D8S77_RS05785 (D8S77_05790)	-	1121130..1121939 (-)	810	WP_003053715.1	purine-nucleoside phosphorylase	-
D8S77_RS05790 (D8S77_05795)	arsC	1121923..1122363 (-)	441	WP_129321971.1	arsenate reductase (glutaredoxin)	-
D8S77_RS05795 (D8S77_05800)	-	1122382..1123593 (-)	1212	WP_129321973.1	phosphopentomutase	-
D8S77_RS05800 (D8S77_05805)	rpiA	1123670..1124353 (-)	684	WP_020905094.1	ribose-5-phosphate isomerase RpiA	-
D8S77_RS05805 (D8S77_05810)	clpC	1124732..1126831 (+)	2100	WP_129321975.1	AAA family ATPase	Regulator
D8S77_RS05810 (D8S77_05815)	-	1126889..1127632 (-)	744	WP_002984942.1	hypothetical protein	-
D8S77_RS05815 (D8S77_05820)	yihA	1127780..1128379 (-)	600	WP_129321977.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
D8S77_RS05820 (D8S77_05825)	clpX	1128389..1129618 (-)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
D8S77_RS05830 (D8S77_05835)	-	1129938..1130435 (-)	498	WP_002984955.1	dihydrofolate reductase	-
D8S77_RS05835 (D8S77_05840)	-	1130515..1131354 (-)	840	WP_011017679.1	thymidylate synthase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77257.39 Da
• Isoelectric Point: 6.0072

>NTDB_id=277740 D8S77_RS05805 WP_129321975.1 1124732..1126831(+) (clpC) [Streptococcus pyogenes strain TSPY556]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTKTSGSNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPDVKKLQAILKEGQLVIRQKDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=277740 D8S77_RS05805 WP_129321975.1 1124732..1126831(+) (clpC) [Streptococcus pyogenes strain TSPY556]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGACATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAATATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGAAAACTTCTGGGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGACGTCAAAAAACTTCAGGCAATTCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• AAA lid domain (AAA_lid_9) (259-353)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.799	100	0.471
clpE	Streptococcus mutans UA159	49.219	91.559	0.451
clpE	Streptococcus pneumoniae TIGR4	49.278	89.127	0.439
clpE	Streptococcus pneumoniae Rx1	49.278	89.127	0.439
clpE	Streptococcus pneumoniae D39	49.278	89.127	0.439
clpE	Streptococcus pneumoniae R6	49.278	89.127	0.439
clpC	Bacillus subtilis subsp. subtilis str. 168	44.511	95.136	0.423
clpC	Streptococcus thermophilus LMD-9	42.79	91.273	0.391
clpC	Streptococcus pneumoniae Rx1	41.871	93.276	0.391
clpC	Streptococcus pneumoniae D39	41.871	93.276	0.391
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.348	93.419	0.386
clpC	Streptococcus thermophilus LMG 18311	42.587	90.701	0.386
clpC	Streptococcus pneumoniae TIGR4	42.857	90.129	0.386
clpC	Streptococcus mutans UA159	41.719	91.559	0.382