Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   D8S76_RS04175 Genome accession   NZ_CP032699
Coordinates   792704..793180 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain TSPY155     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 787704..798180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8S76_RS04140 (D8S76_04135) - 787884..788501 (+) 618 WP_111704669.1 DUF1366 domain-containing protein -
  D8S76_RS04145 (D8S76_04140) - 788511..788807 (+) 297 WP_002990012.1 hypothetical protein -
  D8S76_RS04150 (D8S76_04145) - 788804..788989 (+) 186 WP_002990010.1 holin -
  D8S76_RS04155 (D8S76_04150) - 789090..790424 (+) 1335 WP_011284838.1 GH25 family lysozyme -
  D8S76_RS04160 (D8S76_04155) spei 790698..791375 (+) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  D8S76_RS04165 (D8S76_04160) speh 791401..792111 (+) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  D8S76_RS04175 (D8S76_04170) mutX 792704..793180 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  D8S76_RS04180 (D8S76_04175) - 793238..794419 (+) 1182 WP_002990002.1 AI-2E family transporter -
  D8S76_RS04185 (D8S76_04180) - 794409..795656 (+) 1248 WP_023079234.1 tetratricopeptide repeat protein -
  D8S76_RS04190 (D8S76_04185) fbp54 795715..797367 (-) 1653 WP_014407524.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=277626 D8S76_RS04175 WP_002984880.1 792704..793180(+) (mutX) [Streptococcus pyogenes strain TSPY155]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=277626 D8S76_RS04175 WP_002984880.1 792704..793180(+) (mutX) [Streptococcus pyogenes strain TSPY155]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703