Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   D8S76_RS03695 Genome accession   NZ_CP032699
Coordinates   707589..709688 (-) Length   699 a.a.
NCBI ID   WP_023079078.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY155     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 702589..714688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8S76_RS03665 (D8S76_03660) - 703066..703905 (+) 840 WP_011017679.1 thymidylate synthase -
  D8S76_RS03670 (D8S76_03665) - 703985..704482 (+) 498 WP_002984955.1 dihydrofolate reductase -
  D8S76_RS03675 (D8S76_03670) - 704502..704672 (+) 171 WP_002990165.1 hypothetical protein -
  D8S76_RS03680 (D8S76_03675) clpX 704802..706031 (+) 1230 WP_002984948.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  D8S76_RS03685 (D8S76_03680) yihA 706041..706640 (+) 600 WP_023079094.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  D8S76_RS03690 (D8S76_03685) - 706788..707531 (+) 744 WP_002984942.1 hypothetical protein -
  D8S76_RS03695 (D8S76_03690) clpC 707589..709688 (-) 2100 WP_023079078.1 AAA family ATPase Regulator
  D8S76_RS03700 (D8S76_03695) rpiA 710066..710749 (+) 684 WP_002994002.1 ribose-5-phosphate isomerase RpiA -
  D8S76_RS03705 (D8S76_03700) - 710826..712037 (+) 1212 WP_023079074.1 phosphopentomutase -
  D8S76_RS03710 (D8S76_03705) arsC 712056..712496 (+) 441 WP_023079098.1 arsenate reductase (glutaredoxin) -
  D8S76_RS03715 (D8S76_03710) - 712480..713289 (+) 810 WP_003053715.1 purine-nucleoside phosphorylase -
  D8S76_RS03720 (D8S76_03715) deoD 713874..714587 (+) 714 WP_002990147.1 purine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77413.53 Da        Isoelectric Point: 5.7823

>NTDB_id=277624 D8S76_RS03695 WP_023079078.1 707589..709688(-) (clpC) [Streptococcus pyogenes strain TSPY155]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQKDQ

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=277624 D8S76_RS03695 WP_023079078.1 707589..709688(-) (clpC) [Streptococcus pyogenes strain TSPY155]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTTGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCACTCGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGGTATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGGCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTTACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCCGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTTGCAGCAGT
AGCACGTGCTATTCGACGAAATCGAGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGTTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TCATTACACTTCTTCTACAAGTGTTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAATTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAAAGATCAGTAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-600)

AAA lid domain (AAA_lid_9)

(259-353)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(607-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.084

100

0.474
  clpE Streptococcus mutans UA159

49.531

91.559

0.454
  clpE Streptococcus pneumoniae Rx1

49.438

89.127

0.441
  clpE Streptococcus pneumoniae R6

49.438

89.127

0.441
  clpE Streptococcus pneumoniae D39

49.438

89.127

0.441
  clpE Streptococcus pneumoniae TIGR4

49.438

89.127

0.441
  clpC Bacillus subtilis subsp. subtilis str. 168

44.662

95.136

0.425
  clpC Streptococcus thermophilus LMD-9

42.947

91.273

0.392
  clpC Streptococcus thermophilus LMG 18311

42.79

91.273

0.391
  clpC Streptococcus pneumoniae Rx1

41.871

93.276

0.391
  clpC Streptococcus pneumoniae D39

41.871

93.276

0.391
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.348

93.419

0.386
  clpC Streptococcus pneumoniae TIGR4

42.857

90.129

0.386
  clpC Streptococcus mutans UA159

41.719

91.559

0.382

Multiple sequence alignment