Detailed information NTG0277416

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: MGAS28085_RS08825
• Genome accession: NZ_CP032666
• Coordinates: 1763638..1764405 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28085
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1758638..1769405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS28085_RS08810 (MGAS28085_08810)	hexB	1759156..1761138 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
MGAS28085_RS08815 (MGAS28085_08815)	-	1761233..1762384 (-)	1152	WP_003058754.1	site-specific integrase	-
MGAS28085_RS08820 (MGAS28085_08820)	-	1762633..1762776 (+)	144	WP_011185066.1	putative holin-like toxin	-
MGAS28085_RS08825 (MGAS28085_08825)	irvR	1763638..1764405 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
MGAS28085_RS08830 (MGAS28085_08830)	-	1764559..1764765 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
MGAS28085_RS08835 (MGAS28085_08835)	-	1764799..1764999 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
MGAS28085_RS08840 (MGAS28085_08840)	-	1765020..1765427 (+)	408	WP_002992501.1	hypothetical protein	-
MGAS28085_RS09610	-	1765440..1765562 (+)	123	WP_011285272.1	hypothetical protein	-
MGAS28085_RS08845 (MGAS28085_08845)	-	1765845..1766366 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
MGAS28085_RS08850 (MGAS28085_08850)	-	1766614..1766787 (+)	174	WP_000132665.1	hypothetical protein	-
MGAS28085_RS08855 (MGAS28085_08855)	-	1767005..1767178 (+)	174	WP_000074663.1	plasmid mobilization protein	-
MGAS28085_RS08860 (MGAS28085_08860)	-	1767340..1767771 (+)	432	WP_136302445.1	hypothetical protein	-
MGAS28085_RS08865 (MGAS28085_08865)	-	1767873..1768205 (+)	333	WP_011285276.1	hypothetical protein	-
MGAS28085_RS08870 (MGAS28085_08870)	-	1768205..1768396 (+)	192	WP_021340709.1	hypothetical protein	-
MGAS28085_RS08875 (MGAS28085_08875)	-	1768408..1768737 (+)	330	WP_003058810.1	hypothetical protein	-
MGAS28085_RS08880 (MGAS28085_08880)	-	1768740..1769012 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=277416 MGAS28085_RS08825 WP_003058809.1 1763638..1764405(-) (irvR) [Streptococcus pyogenes strain MGAS28085]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=277416 MGAS28085_RS08825 WP_003058809.1 1763638..1764405(-) (irvR) [Streptococcus pyogenes strain MGAS28085]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4