Detailed information
Bioinformatically predicted
Overview
| Name | sxy/tfoX | Type | Regulator |
| Locus tag | C6W74_RS12640 | Genome accession | NZ_CP027454 |
| Coordinates | 2485198..2485827 (+) | Length | 209 a.a. |
| NCBI ID | WP_000841914.1 | Uniprot ID | A0AAP9MNK0 |
| Organism | Escherichia coli strain 2014C-4423 | ||
| Function | positive regulator of competence gene (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2465424..2500893 | 2485198..2485827 | within | 0 |
Gene organization within MGE regions
Location: 2465424..2500893
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6W74_RS12545 | elfG | 2465858..2466928 (+) | 1071 | WP_106901531.1 | fimbrial protein | - |
| C6W74_RS12550 | ycbU | 2466940..2467482 (+) | 543 | WP_000730616.1 | fimbrial protein | - |
| C6W74_RS12555 | ycbV | 2467490..2468005 (+) | 516 | WP_000919489.1 | fimbrial protein | - |
| C6W74_RS12560 | ycbF | 2467971..2468708 (+) | 738 | WP_001111474.1 | fimbrial chaperone | - |
| C6W74_RS12565 | pyrD | 2468819..2469829 (+) | 1011 | WP_001370288.1 | quinone-dependent dihydroorotate dehydrogenase | - |
| C6W74_RS12570 | zapC | 2470003..2470545 (+) | 543 | WP_001338438.1 | cell division protein ZapC | - |
| C6W74_RS12575 | ycbX | 2470542..2471651 (-) | 1110 | WP_000224270.1 | 6-N-hydroxylaminopurine resistance protein YcbX | - |
| C6W74_RS12580 | rlmKL | 2471894..2474002 (+) | 2109 | WP_001086532.1 | bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL | - |
| C6W74_RS12585 | uup | 2474014..2475921 (+) | 1908 | WP_000053123.1 | ABC transporter ATP-binding protein | - |
| C6W74_RS12590 | pqiA | 2476051..2477304 (+) | 1254 | WP_000333176.1 | membrane integrity-associated transporter subunit PqiA | - |
| C6W74_RS12595 | pqiB | 2477309..2478949 (+) | 1641 | WP_000445533.1 | intermembrane transport protein PqiB | - |
| C6W74_RS12600 | pqiC | 2478946..2479509 (+) | 564 | WP_000759120.1 | membrane integrity-associated transporter subunit PqiC | - |
| C6W74_RS12605 | rmf | 2479764..2479931 (+) | 168 | WP_000828648.1 | ribosome modulation factor | - |
| C6W74_RS12610 | fabA | 2480001..2480519 (-) | 519 | WP_000227927.1 | bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase | - |
| C6W74_RS12615 | ycbZ | 2480588..2482348 (-) | 1761 | WP_000156526.1 | Lon protease family protein | - |
| C6W74_RS12620 | matP | 2482534..2482986 (+) | 453 | WP_000877158.1 | macrodomain Ter protein MatP | - |
| C6W74_RS12625 | ompA | 2483061..2484113 (-) | 1053 | WP_000750419.1 | porin OmpA | - |
| C6W74_RS12635 | sulA | 2484470..2484979 (-) | 510 | WP_000288710.1 | SOS-induced cell division inhibitor SulA | - |
| C6W74_RS12640 | sxy/tfoX | 2485198..2485827 (+) | 630 | WP_000841914.1 | CRP-S regulon transcriptional coactivator Sxy | Regulator |
| C6W74_RS12645 | yccS | 2485790..2487952 (-) | 2163 | WP_000875061.1 | YccS family putative transporter | - |
| C6W74_RS12650 | yccF | 2487962..2488408 (-) | 447 | WP_001261235.1 | YccF domain-containing protein | - |
| C6W74_RS12655 | helD | 2488531..2490585 (+) | 2055 | WP_001295354.1 | DNA helicase IV | - |
| C6W74_RS12660 | mgsA | 2490617..2491075 (-) | 459 | WP_000424181.1 | methylglyoxal synthase | - |
| C6W74_RS12665 | yccT | 2491171..2491833 (-) | 663 | WP_000847791.1 | DUF2057 family protein | - |
| C6W74_RS12670 | yccU | 2492006..2492419 (+) | 414 | WP_000665217.1 | CoA-binding protein | - |
| C6W74_RS12675 | hspQ | 2492464..2492781 (-) | 318 | WP_001295356.1 | heat shock protein HspQ | - |
| C6W74_RS12680 | rlmI | 2492839..2494029 (-) | 1191 | WP_000116288.1 | 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI | - |
| C6W74_RS12685 | yccX | 2494124..2494402 (+) | 279 | WP_000048233.1 | acylphosphatase | - |
| C6W74_RS12690 | tusE | 2494399..2494728 (-) | 330 | WP_000904442.1 | sulfurtransferase TusE | - |
| C6W74_RS12695 | yccA | 2494819..2495478 (-) | 660 | WP_000375136.1 | FtsH protease modulator YccA | - |
| C6W74_RS12700 | - | 2495886..2496905 (-) | 1020 | WP_001370339.1 | tyrosine-type recombinase/integrase | - |
| C6W74_RS12705 | - | 2496883..2497125 (-) | 243 | WP_000273151.1 | DUF4224 domain-containing protein | - |
| C6W74_RS12710 | - | 2497193..2498602 (-) | 1410 | Protein_2328 | 3'-5' exoribonuclease | - |
| C6W74_RS12715 | - | 2498635..2500191 (-) | 1557 | WP_001066419.1 | IS66 family transposase | - |
| C6W74_RS12720 | tnpB | 2500211..2500558 (-) | 348 | WP_000631725.1 | IS66 family insertion sequence element accessory protein TnpB | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 24130.97 Da Isoelectric Point: 9.2180
>NTDB_id=277341 C6W74_RS12640 WP_000841914.1 2485198..2485827(+) (sxy/tfoX) [Escherichia coli strain 2014C-4423]
MKSPSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
MKSPSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
Nucleotide
Download Length: 630 bp
>NTDB_id=277341 C6W74_RS12640 WP_000841914.1 2485198..2485827(+) (sxy/tfoX) [Escherichia coli strain 2014C-4423]
ATGAAAAGCCCCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
ATGAAAAGCCCCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sxy/tfoX | Escherichia coli BW25113 strain K-12 |
99.522 |
100 |
0.995 |