Detailed information NTG0276922

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: CFK78_RS03525
• Genome accession: NZ_CP032633
• Coordinates: 747066..749669 (+)
• Length: 867 a.a.
• NCBI ID: WP_016264638.1
• Uniprot ID: -
• Organism: Latilactobacillus sakei strain ZFM220
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 742066..754669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFK78_RS03515 (CFK78_03515)	-	744232..746061 (+)	1830	WP_016264636.1	APC family permease	-
CFK78_RS03520 (CFK78_03520)	-	746238..747044 (+)	807	WP_016264637.1	TIGR00282 family metallophosphoesterase	-
CFK78_RS03525 (CFK78_03525)	hexA	747066..749669 (+)	2604	WP_016264638.1	DNA mismatch repair protein MutS	Machinery gene
CFK78_RS03530 (CFK78_03530)	hexB	749693..751654 (+)	1962	WP_035146236.1	DNA mismatch repair endonuclease MutL	Machinery gene
CFK78_RS03535 (CFK78_03535)	-	751654..752199 (+)	546	WP_016264640.1	Maf family protein	-
CFK78_RS03540 (CFK78_03540)	-	752212..752775 (+)	564	WP_016264641.1	TIGR00730 family Rossman fold protein	-
CFK78_RS03545 (CFK78_03545)	ruvA	753026..753637 (+)	612	WP_016264642.1	Holliday junction branch migration protein RuvA	Machinery gene
CFK78_RS03550 (CFK78_03550)	ruvB	753650..754657 (+)	1008	WP_016264643.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene

Sequence

Protein

• Length: 867 a.a.
• Molecular weight: 96876.71 Da
• Isoelectric Point: 5.2556

>NTDB_id=276922 CFK78_RS03525 WP_016264638.1 747066..749669(+) (hexA) [Latilactobacillus sakei strain ZFM220]
MPQKTKETPMMAQYQKVKDQYPDAFLFYRLGDFYELFNDDAVKASQLLELTLTARNKNAADPIPMCGVPHHAAQNYIDIL
VDQGYKVAICEQMEDPKTAKGMVKREVVQLVTPGTVMDEKAGHAKQNNYLTAVVAQGDQFGFAYTDLSTGEMKVSQISSL
DVLLNEMLSLQTKEVVVNHDVPSEVVQAFVQQQILVSYQDEGADTAEVSFVSQNISQPLALAVIKQLVVYLATTQKRHLG
HLQRAQAYEPSQYLKLDHSAKMNLELTASLRTGHKSGTLLWLLDETKTAMGGRLLKQWLERPLLDLNQIKNRQNQVASFL
QHYFERTNLQEALTKVYDLERLAGRVAFGSVNGRDLIQLKTSLEQIPKIKDVLTGINETQAFDQALTRLDPVDDVRTLIE
TAINPDSPISVTDGGIIQDGYDEQLDQYRNAMSNGKQWLAQLEAQEREATGIHNLKIGFNRVFGYYIEVTRANLSSLPEG
RYERKQTLTNAERFITPELKEKEQLILEAEERSTALEYELFTQVREQVKLQIERLQTLAKGVAALDVLQSFAVVSESYHY
VQPTLRTDSREIDLVDGRHPVVEKVLGRQKYIPNAVQMGKETDMLLITGPNMSGKSTYMRQLALTVIMAQMGCFVPAKSA
NLPVFDQIFTRIGAADDLISGQSTFMVEMMEANRAIMSATANSLILFDEIGRGTATYDGMALAQAIIEYIHDHVHAKTLF
STHYHELTALADTLTALRNVHVGAVEENGELVFLHKMLAGPADKSYGIHVAKLAGMPETLLQRADVILGQLEDKPKAPVQ
PEIVVPAQPTAAAVEEQMALFEPEVAAPVDKKTDKVVAAIKNFDLMSATPLEALNQLYEWQKQLNKH

Nucleotide

• Length: 2604 bp

>NTDB_id=276922 CFK78_RS03525 WP_016264638.1 747066..749669(+) (hexA) [Latilactobacillus sakei strain ZFM220]
ATGCCGCAAAAAACAAAAGAAACGCCAATGATGGCCCAATATCAAAAGGTTAAGGATCAATATCCAGACGCCTTTTTATT
TTATAGATTGGGTGATTTTTACGAATTATTCAATGATGATGCTGTTAAAGCATCACAACTTTTAGAATTAACGCTGACAG
CGCGTAATAAGAATGCAGCAGACCCCATTCCGATGTGTGGTGTGCCCCATCATGCAGCGCAAAACTACATTGATATTTTA
GTGGATCAAGGTTACAAGGTCGCCATTTGTGAGCAGATGGAAGATCCTAAAACGGCTAAGGGCATGGTCAAACGCGAAGT
TGTCCAATTAGTAACACCTGGGACCGTGATGGACGAAAAAGCCGGTCACGCTAAACAAAATAATTATTTAACGGCAGTCG
TTGCACAAGGCGATCAATTTGGCTTTGCCTATACGGATTTATCCACAGGTGAAATGAAGGTTAGCCAAATCAGTAGTTTA
GATGTGTTATTAAACGAAATGTTGAGTTTACAAACCAAAGAAGTGGTTGTGAACCATGATGTCCCAAGCGAAGTCGTTCA
AGCCTTTGTCCAACAACAAATCTTGGTTTCTTATCAAGATGAGGGGGCCGATACGGCAGAGGTCAGTTTTGTTTCTCAAA
ATATCTCACAACCACTAGCATTAGCCGTCATTAAACAGTTAGTTGTTTATTTAGCAACGACGCAAAAGCGGCACTTGGGC
CATTTACAACGCGCCCAAGCCTATGAACCTTCTCAATACTTGAAGTTGGATCATTCGGCTAAGATGAACCTCGAATTAAC
GGCTTCATTACGAACTGGCCATAAGAGTGGGACGTTATTGTGGCTACTGGATGAAACAAAGACTGCGATGGGTGGTCGTT
TATTAAAACAATGGTTGGAACGACCATTGTTGGATTTAAACCAGATTAAGAACCGGCAAAACCAAGTCGCTAGTTTCTTA
CAGCACTATTTTGAAAGGACGAACCTTCAAGAAGCCCTAACCAAGGTTTATGATTTGGAACGTCTAGCGGGTCGCGTTGC
TTTTGGGAGCGTTAATGGTCGCGATTTGATTCAATTAAAAACATCCTTAGAACAGATTCCAAAGATTAAAGATGTTTTGA
CGGGCATTAACGAAACGCAGGCTTTTGATCAAGCGTTAACGCGTTTGGATCCAGTTGATGATGTGCGGACGTTAATTGAA
ACAGCGATTAACCCGGATTCACCGATTTCAGTGACTGATGGCGGGATTATTCAAGATGGTTACGACGAACAACTTGATCA
ATACCGCAATGCGATGTCTAACGGCAAGCAGTGGTTGGCGCAATTAGAGGCGCAAGAACGAGAAGCCACGGGCATTCATA
ATTTGAAAATCGGCTTTAACCGCGTCTTTGGGTATTATATCGAAGTCACGCGGGCTAACTTGAGTTCATTACCGGAAGGG
CGGTATGAACGCAAACAAACGTTAACCAACGCCGAACGATTCATCACACCGGAACTAAAAGAAAAAGAACAACTGATTTT
AGAGGCGGAAGAACGCTCAACCGCTTTAGAATACGAATTGTTTACCCAAGTTCGGGAACAAGTGAAGTTACAGATTGAAC
GGCTCCAAACATTGGCTAAAGGCGTAGCGGCCCTAGATGTCTTGCAAAGTTTTGCGGTCGTCAGCGAAAGCTACCACTAT
GTCCAACCAACATTAAGAACTGATAGTCGCGAAATTGATTTAGTCGATGGCCGTCATCCGGTGGTTGAAAAGGTATTGGG
ACGCCAAAAATATATCCCCAATGCTGTTCAAATGGGCAAAGAAACGGATATGTTATTAATTACCGGACCTAATATGTCTG
GTAAAAGTACCTACATGCGGCAATTGGCCTTAACGGTCATCATGGCGCAAATGGGTTGTTTTGTACCTGCCAAGTCAGCG
AACTTGCCTGTATTTGATCAAATTTTTACCCGCATTGGCGCGGCAGATGATTTGATTTCAGGACAAAGTACGTTTATGGT
AGAAATGATGGAAGCCAACCGTGCAATTATGAGTGCGACCGCCAATAGTTTAATTCTTTTCGATGAAATTGGTCGGGGAA
CGGCAACTTACGATGGAATGGCCTTGGCACAAGCGATTATCGAATATATCCATGATCACGTCCACGCCAAGACGCTCTTT
TCAACGCATTATCATGAATTGACGGCTTTAGCCGATACGTTGACCGCCCTCCGTAACGTGCATGTTGGTGCGGTTGAGGA
AAACGGCGAGTTGGTCTTCTTACACAAGATGTTGGCCGGACCTGCGGATAAGTCTTACGGGATTCATGTCGCTAAACTAG
CGGGCATGCCAGAAACCTTATTACAACGGGCCGATGTTATTTTAGGTCAGTTAGAAGATAAACCAAAAGCACCGGTGCAA
CCAGAAATAGTCGTACCAGCACAACCGACTGCAGCGGCTGTCGAAGAACAGATGGCGCTTTTTGAACCAGAAGTGGCGGC
CCCGGTCGATAAGAAAACAGATAAAGTGGTAGCGGCAATTAAGAATTTTGATTTGATGAGCGCCACACCACTAGAAGCCC
TCAATCAATTATATGAGTGGCAAAAGCAATTAAATAAACATTAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-119)

• MutS domain II (MutS_II) (128-243)

• MutS family domain IV (MutS_IV) (420-512)

• MutS domain V (MutS_V) (605-792)

• MutS domain III (MutS_III) (263-552)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	52.079	99.885	0.52
mutS	Pseudomonas stutzeri strain ATCC 17587	38.655	100	0.391