Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   SSA_RS10765 Genome accession   NC_009009
Coordinates   2198769..2201198 (-) Length   809 a.a.
NCBI ID   WP_011837612.1    Uniprot ID   A3CQV9
Organism   Streptococcus sanguinis SK36     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2193769..2206198
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS10735 (SSA_2193) - 2194101..2194883 (-) 783 WP_011837608.1 NUDIX domain-containing protein -
  SSA_RS10740 (SSA_2194) pnuC 2194938..2195753 (-) 816 WP_011837609.1 nicotinamide riboside transporter PnuC -
  SSA_RS10745 (SSA_2195) - 2195775..2196833 (-) 1059 WP_011837610.1 AAA family ATPase -
  SSA_RS10750 (SSA_2196) - 2197019..2197420 (-) 402 WP_002894007.1 DUF4430 domain-containing protein -
  SSA_RS10755 (SSA_2197) - 2197404..2197889 (-) 486 WP_002899229.1 hypothetical protein -
  SSA_RS10760 (SSA_2198) - 2197932..2198675 (-) 744 WP_002917823.1 DUF4272 domain-containing protein -
  SSA_RS10765 (SSA_2199) clpC 2198769..2201198 (-) 2430 WP_011837612.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SSA_RS10770 (SSA_2200) - 2201199..2201663 (-) 465 WP_002899234.1 CtsR family transcriptional regulator -
  SSA_RS10775 (SSA_2201) - 2201809..2202297 (+) 489 WP_164925997.1 hypothetical protein -
  SSA_RS10780 (SSA_2202) tsf 2202397..2203440 (-) 1044 WP_002894014.1 translation elongation factor Ts -
  SSA_RS10785 (SSA_2203) rpsB 2203513..2204295 (-) 783 WP_002894015.1 30S ribosomal protein S2 -
  SSA_RS10795 (SSA_2204) - 2204803..2205567 (+) 765 WP_011837614.1 hypothetical protein -
  SSA_RS10800 (SSA_2205) nusG 2205654..2206190 (-) 537 WP_002894018.1 transcription termination/antitermination protein NusG -

Sequence

Protein


Download         Length: 809 a.a.        Molecular weight: 89660.22 Da        Isoelectric Point: 5.1953

>NTDB_id=27550 SSA_RS10765 WP_011837612.1 2198769..2201198(-) (clpC) [Streptococcus sanguinis SK36]
MKYSKALIESLEAAQLLAGHFTTDYLESWHLLIALANNPYSVAGSVLNEFPVEVDGFEEAAFQITGQAYQKDGHFELLPF
SYRLEELFEEAGQVAEAVRAKHVGTEHVLLAMLFDRGTLASRILEFTGFSYEDKEQGPKISDLRKVLEQRAGWGKEDIKA
IRSLNKGVMAAKQTMANMMGMPASTSGGLEDYTRDLTELARDGRLEPVIGRDQEISRIVQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPAELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVSIEEPNVADSIAILQGLRKSYEDHHKVQISDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVQNRGPQNYEQSDLTPVDQALMAADFKKVSQLLEQEQQPKLYKLKVEEDDVL
ATLSGLSGIPVQKLTQTDAKKYLNLETELHKRVIGQDEAISAISRAIRRNQSGIRSSKRPIGSFMFLGPTGVGKTELAKA
LAESLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
QLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDIRLDHANMEKRMLEELKKAYRPEFINRIDEKVVFHSLSAE
DMQEVVKVMVKPLIASLAEKGIELKFQTSALKLLAQEGYDVEMGARPLRRTLQTQVEDKLSELLLTGDLMTGQTLKVGVK
AGQLKFEVA

Nucleotide


Download         Length: 2430 bp        

>NTDB_id=27550 SSA_RS10765 WP_011837612.1 2198769..2201198(-) (clpC) [Streptococcus sanguinis SK36]
ATGAAATACTCAAAAGCCTTAATAGAAAGCTTGGAAGCAGCCCAGCTCTTGGCCGGCCATTTTACGACAGATTATCTGGA
ATCATGGCATCTGCTGATTGCTCTGGCTAATAATCCCTACAGCGTTGCTGGCTCAGTTCTCAATGAGTTTCCTGTGGAAG
TTGATGGATTTGAAGAAGCGGCTTTTCAGATTACTGGTCAGGCTTATCAGAAAGACGGTCACTTCGAGCTGCTGCCTTTT
TCTTATCGCTTAGAGGAGTTGTTTGAGGAGGCGGGCCAGGTTGCAGAAGCTGTTCGGGCTAAGCATGTAGGTACTGAACA
TGTGCTGCTGGCTATGTTATTTGACCGGGGGACCTTGGCCTCTCGTATTCTGGAATTTACTGGCTTTAGCTACGAGGACA
AGGAGCAGGGACCGAAAATCAGTGATTTGCGAAAGGTCTTGGAGCAGCGAGCTGGCTGGGGCAAGGAAGATATCAAGGCT
ATTCGCAGTCTGAATAAGGGAGTAATGGCCGCTAAGCAGACCATGGCCAATATGATGGGTATGCCAGCTTCTACTAGCGG
TGGTCTGGAAGACTACACCCGTGATCTGACGGAGCTGGCTAGAGATGGCCGATTGGAGCCCGTCATTGGCCGCGATCAAG
AAATTTCACGGATAGTTCAGATTCTCAGTCGTAAGACTAAAAACAATCCAGTGCTGGTTGGAGATGCTGGGGTTGGTAAG
ACAGCTCTGGCTTTAGGACTGGCTCAGCGTGTAGCGGCTGGTCAGGTTCCGGCTGAACTTGCTAAGATGCGGGTTTTGGA
GCTGGACTTGATGAATGTAGTCGCTGGCACTCGCTTTCGCGGAGACTTCGAGGAGCGGATGAACAACATCATCAATGACA
TTGAAGAAGATGGTCATGTCATTCTCTTCATCGATGAGCTTCATACTATCATGGGCTCTGGCAGCGGTATTGACTCGACC
TTGGATGCGGCCAATATCCTGAAACCGGCTCTAGCTCGCGGAACTCTGCGGACAGTTGGCGCTACGACGCAGGAAGAGTA
CCAGAAACATATTGAAAAAGATGCGGCCCTTTCCCGGCGTTTTGCCAAGGTCAGCATAGAAGAGCCAAATGTGGCTGACA
GCATTGCTATTTTGCAAGGTCTGAGAAAGAGCTATGAGGACCATCACAAGGTACAGATTAGTGATCAGGCTATTGAGACG
GCGGTGAAATACGCCCATCGCTATCTGACTAGCAAGCATCTGCCAGACTCTGCCATTGATCTTTTGGACGAGGCCAGTGC
AACAGTGCAGAACAGAGGACCGCAAAATTACGAGCAGTCGGATTTGACGCCAGTAGATCAAGCCTTGATGGCAGCGGATT
TTAAAAAGGTTTCACAACTGCTTGAGCAAGAGCAGCAACCTAAGCTCTATAAACTGAAAGTGGAAGAAGACGATGTTTTG
GCTACTCTGAGTGGCTTGTCTGGTATTCCAGTGCAGAAGCTGACTCAGACAGATGCGAAGAAATACCTCAATTTGGAAAC
AGAACTGCATAAACGCGTGATTGGGCAGGACGAGGCGATTTCAGCTATCAGCCGAGCTATCCGACGGAACCAGTCTGGTA
TCCGCAGCAGCAAGCGGCCGATTGGCTCCTTTATGTTCCTAGGTCCGACAGGAGTCGGGAAGACAGAGCTAGCCAAGGCC
TTGGCCGAAAGTCTCTTTGATGACGAGTCTGCTCTCATCCGCTTTGATATGAGTGAGTACATGGAGAAATTCGCGGCTAG
CCGCCTCAATGGAGCGCCTCCAGGCTATGTAGGCTATGAAGAAGGGGGGGAGCTGACGGAAAAGGTGCGCAACAGACCTT
ATTCTGTCCTGCTCTTTGACGAGGTGGAAAAGGCGCACCCGGATATTTTCAATGTTCTCCTGCAGGTCTTGGATGATGGT
CAGTTGACTGATAGCAAGGGCCGCAAGGTGGACTTCTCCAACACGATTATTATCATGACCAGCAATCTGGGGGCAACTAG
TTTGCGGGATGATAAGACGGTGGGCTTTGGAGCGCGGGATATTCGCTTGGACCATGCCAATATGGAAAAACGGATGCTGG
AAGAGCTTAAGAAAGCATATAGACCGGAGTTTATCAACCGTATTGACGAGAAGGTAGTTTTCCACAGCTTATCTGCAGAA
GATATGCAGGAAGTGGTCAAGGTTATGGTCAAACCGCTCATTGCCAGTCTCGCCGAGAAGGGAATTGAGCTGAAGTTTCA
GACTAGTGCCCTTAAGCTACTGGCTCAGGAAGGCTACGATGTGGAAATGGGGGCACGGCCATTGCGCCGCACTCTGCAGA
CCCAGGTAGAGGACAAACTATCTGAACTCCTCTTGACAGGAGATTTGATGACGGGTCAAACTCTTAAGGTCGGGGTCAAG
GCTGGCCAACTCAAGTTCGAAGTGGCCTAG

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(371-463)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-60)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(101-133)

AAA domain (Cdc48 subfamily) (AAA_2)

(539-710)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(717-797)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CQV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

77.778

100

0.779
  clpC Streptococcus pneumoniae D39

77.778

100

0.779
  clpC Streptococcus pneumoniae TIGR4

77.778

100

0.779
  clpC Streptococcus mutans UA159

67.813

100

0.682
  clpC Streptococcus thermophilus LMG 18311

66.667

100

0.67
  clpC Streptococcus thermophilus LMD-9

66.544

100

0.669
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.605

100

0.517
  clpC Bacillus subtilis subsp. subtilis str. 168

45.568

99.011

0.451
  clpE Streptococcus mutans UA159

47.65

76.267

0.363

Multiple sequence alignment