Detailed information NTG0027548

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPH_RS00675
• Genome accession: NC_010380
• Coordinates: 115263..116156 (+)
• Length: 297 a.a.
• NCBI ID: WP_000343888.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae Hungary19A-6
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 110263..121156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPH_RS00635 (SPH_0135)	-	110579..111748 (+)	1170	WP_000366376.1	pyridoxal phosphate-dependent aminotransferase	-
SPH_RS00640 (SPH_0136)	recO	111745..112515 (+)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
SPH_RS00645 (SPH_0137)	plsX	112512..113504 (+)	993	WP_000717456.1	phosphate acyltransferase PlsX	-
SPH_RS00650 (SPH_0138)	-	113510..113743 (+)	234	WP_000136447.1	acyl carrier protein	-
SPH_RS00655 (SPH_0139)	-	113789..114079 (+)	291	Protein_123	transposase family protein	-
SPH_RS00660 (SPH_0140)	blpU	114282..114512 (+)	231	WP_001093075.1	bacteriocin-like peptide BlpU	-
SPH_RS14155 (SPH_0141)	-	114515..114640 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
SPH_RS13780	-	115048..115242 (+)	195	WP_000756776.1	hypothetical protein	-
SPH_RS00675 (SPH_0142)	comR	115263..116156 (+)	894	WP_000343888.1	XRE family transcriptional regulator	Regulator
SPH_RS00680 (SPH_0143)	-	116699..116995 (+)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
SPH_RS00685 (SPH_0144)	-	117002..118138 (+)	1137	WP_000698828.1	hypothetical protein	-
SPH_RS12055	-	118135..118617 (+)	483	WP_001232094.1	stage II sporulation protein M	-
SPH_RS00695 (SPH_0146)	-	118614..119210 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
SPH_RS00700 (SPH_0147)	-	119191..119682 (+)	492	WP_000671990.1	hypothetical protein	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34517.01 Da
• Isoelectric Point: 4.6498

>NTDB_id=27548 SPH_RS00675 WP_000343888.1 115263..116156(+) (comR) [Streptococcus pneumoniae Hungary19A-6]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=27548 SPH_RS00675 WP_000343888.1 115263..116156(+) (comR) [Streptococcus pneumoniae Hungary19A-6]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37