Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SSA_RS03965 Genome accession   NC_009009
Coordinates   774999..775859 (+) Length   286 a.a.
NCBI ID   WP_004187660.1    Uniprot ID   A0A3R9HIX5
Organism   Streptococcus sanguinis SK36     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 769999..780859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS03935 (SSA_0787) - 770257..771138 (+) 882 WP_002895995.1 F0F1 ATP synthase subunit gamma -
  SSA_RS03940 (SSA_0788) atpD 771177..772583 (+) 1407 WP_002897903.1 F0F1 ATP synthase subunit beta -
  SSA_RS03945 (SSA_0789) - 772591..773013 (+) 423 WP_002904155.1 F0F1 ATP synthase subunit epsilon -
  SSA_RS03950 (SSA_0790) - 773187..773417 (+) 231 WP_002895990.1 DUF1146 family protein -
  SSA_RS03955 (SSA_0791) murA 773485..774765 (+) 1281 WP_011836719.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SSA_RS03960 (SSA_0792) - 774758..774940 (+) 183 WP_002912082.1 DNA-directed RNA polymerase subunit beta -
  SSA_RS03965 (SSA_0793) endA 774999..775859 (+) 861 WP_004187660.1 DNA/RNA non-specific endonuclease Machinery gene
  SSA_RS03970 (SSA_0794) - 776036..776755 (+) 720 WP_002912084.1 matrixin family metalloprotease -
  SSA_RS03975 (SSA_0795) - 776760..777125 (+) 366 WP_011836720.1 hypothetical protein -
  SSA_RS03980 (SSA_0796) - 777225..779120 (+) 1896 WP_011836721.1 ABC-F family ATP-binding cassette domain-containing protein -
  SSA_RS03985 (SSA_0797) - 779661..780524 (+) 864 WP_011836722.1 transcriptional regulator -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31237.77 Da        Isoelectric Point: 9.8976

>NTDB_id=27520 SSA_RS03965 WP_004187660.1 774999..775859(+) (endA) [Streptococcus sanguinis SK36]
MKRKTSQKRNSKSLQGWAGLTLALILALAGYFWGQDGQQPLQSPNSEIRVGQVQDQGTPSQELAESVLTDAVRAQLKGSI
EWNGAGAFIVNGNRTDLDAGISSKPYADNKTKFVQGQAIPTVANAFLSKSTRQYKKREETGNANTSWVPAGWHQLKNLSG
EYNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWSNQANEADSTGQNYYETKIRKALDKNKRVRYRVTLIYATET
DLVPVGSHLEAKSSDGSLEFNVFIPNVQKGIRLDYNSGRVSQETGS

Nucleotide


Download         Length: 861 bp        

>NTDB_id=27520 SSA_RS03965 WP_004187660.1 774999..775859(+) (endA) [Streptococcus sanguinis SK36]
ATGAAAAGAAAGACTAGTCAGAAAAGGAATTCTAAGAGCCTGCAAGGCTGGGCTGGGCTGACTCTGGCTTTGATTTTAGC
TCTGGCTGGCTATTTCTGGGGACAGGACGGTCAGCAGCCACTTCAGAGTCCAAATTCAGAAATCAGAGTTGGGCAAGTCC
AAGATCAGGGCACCCCTAGTCAGGAACTGGCTGAGAGCGTTCTGACGGATGCTGTCCGAGCTCAGCTTAAAGGCAGCATT
GAATGGAATGGAGCTGGCGCCTTTATCGTGAATGGGAATAGGACAGACTTGGATGCGGGGATTTCTAGCAAACCCTACGC
TGACAATAAGACCAAGTTTGTACAAGGGCAAGCTATTCCGACGGTGGCGAATGCCTTTTTATCCAAGTCTACCCGCCAGT
ACAAAAAACGGGAAGAAACTGGAAATGCCAACACTTCATGGGTACCGGCAGGCTGGCATCAACTCAAGAACCTCTCTGGT
GAGTACAATCATGCTGTGGACCGCGGACATCTCTTGGCCTATTCACTGATTGGTGGTTTGAAGGGCTTTGATGCCTCCAC
CAGCAATCCTGCCAATATCGCTGTGCAGACGGCCTGGTCCAACCAAGCCAATGAGGCGGATTCGACAGGGCAGAATTACT
ATGAGACAAAGATCCGTAAGGCTTTGGATAAGAACAAGCGGGTGCGCTACCGGGTAACCTTGATTTATGCCACGGAGACG
GATTTAGTACCGGTTGGGTCACATTTAGAGGCCAAGTCCAGCGATGGCAGTCTGGAATTTAATGTCTTTATCCCGAATGT
GCAAAAAGGGATTCGCTTGGACTATAATAGTGGCAGGGTCAGTCAGGAGACGGGTTCTTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(103-256)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9HIX5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

74.439

77.972

0.58
  endA Streptococcus pneumoniae D39

74.439

77.972

0.58
  endA Streptococcus pneumoniae R6

74.439

77.972

0.58
  endA Streptococcus pneumoniae TIGR4

74.439

77.972

0.58

Multiple sequence alignment