Detailed information NTG0027511

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSA_RS03190
• Genome accession: NC_009009
• Coordinates: 616229..617272 (+)
• Length: 347 a.a.
• NCBI ID: WP_011836629.1
• Uniprot ID: A3CLL1
• Organism: Streptococcus sanguinis SK36
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 611229..622272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSA_RS03155 (SSA_0618)	-	611770..612063 (-)	294	WP_002910360.1	DUF5960 family protein	-
SSA_RS03160 (SSA_0620)	-	612041..612415 (-)	375	WP_011836625.1	hypothetical protein	-
SSA_RS03165 (SSA_0621)	-	612412..613827 (-)	1416	WP_011836626.1	Y-family DNA polymerase	-
SSA_RS03170 (SSA_0622)	-	613832..614509 (-)	678	WP_011836627.1	helix-turn-helix domain-containing protein	-
SSA_RS03175 (SSA_0623)	-	614652..615140 (+)	489	WP_002921995.1	YcxB family protein	-
SSA_RS03180 (SSA_0624)	rsmD	615210..615758 (+)	549	WP_033179123.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSA_RS03185 (SSA_0625)	coaD	615748..616242 (+)	495	WP_002921993.1	pantetheine-phosphate adenylyltransferase	-
SSA_RS03190 (SSA_0626)	sepM	616229..617272 (+)	1044	WP_011836629.1	SepM family pheromone-processing serine protease	Regulator
SSA_RS03195 (SSA_0627)	-	617454..618035 (+)	582	WP_011836630.1	YutD family protein	-
SSA_RS03200 (SSA_0628)	rlmN	618032..619120 (+)	1089	WP_002911938.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSA_RS03205 (SSA_0629)	-	619107..619646 (+)	540	WP_011836631.1	VanZ family protein	-
SSA_RS03210 (SSA_0631)	trpB	620012..621193 (+)	1182	WP_011836632.1	tryptophan synthase subunit beta	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38065.23 Da
• Isoelectric Point: 5.0267

>NTDB_id=27511 SSA_RS03190 WP_011836629.1 616229..617272(+) (sepM) [Streptococcus sanguinis SK36]
MKRIKKYLWPTVIGVTIAFFIAAFWVRLPYYIEVPGGAEDVRQVLLVDNKADKEAGSYNFVTVGVEQATFAHLVYAWLTP
FTDIYSAKDMTGGSTDEEFNRINQFYMETSQNMAKYQGLTTAGKEIKMDYLGVYVLQVADNSTFKGVLNIADTVTGVNDK
TFESSEELVKYVNSQKLGDKIKVTFQEDGQEKSATGKVIKLENGKNGIGISLIDRTEVSSSIPITFSTEGIGGPSAGLMF
SLAIYTQLADPTLRDGRDIAGTGSISREGEVGEIGGIDKKVVSAAQSGADIFFAPNNELTEEEKKLSPNGKNNYQTALET
AKKIKTDMKIVPVKTLQDAIDYLKKNK

Nucleotide

• Length: 1044 bp

>NTDB_id=27511 SSA_RS03190 WP_011836629.1 616229..617272(+) (sepM) [Streptococcus sanguinis SK36]
ATGAAAAGAATTAAGAAGTATCTATGGCCGACGGTCATTGGCGTCACTATTGCCTTTTTTATAGCAGCTTTTTGGGTTCG
TCTGCCTTATTATATAGAAGTTCCTGGTGGTGCCGAGGATGTTCGGCAGGTCTTGCTGGTTGATAATAAGGCCGACAAGG
AAGCGGGTTCCTACAACTTTGTGACGGTCGGAGTAGAGCAGGCAACCTTTGCTCATCTGGTCTATGCTTGGCTGACCCCT
TTTACAGATATTTATTCCGCCAAGGATATGACAGGGGGATCCACGGATGAGGAGTTCAATCGGATCAACCAGTTTTACAT
GGAAACATCACAAAATATGGCTAAATATCAAGGGTTGACGACAGCTGGTAAAGAGATCAAAATGGACTATCTGGGAGTTT
ATGTCCTACAGGTGGCTGATAACTCAACCTTCAAGGGAGTTCTCAATATTGCTGATACGGTAACTGGTGTCAATGATAAG
ACATTTGAAAGCTCTGAGGAACTGGTCAAGTATGTCAACTCGCAGAAGCTTGGGGATAAAATCAAGGTGACTTTCCAAGA
AGATGGTCAGGAGAAATCGGCAACCGGTAAGGTCATCAAGTTGGAGAACGGTAAGAACGGGATTGGGATTAGTCTGATAG
ACCGGACGGAAGTCAGCAGCAGTATTCCGATTACATTTTCAACTGAGGGTATCGGCGGTCCCAGTGCTGGTCTCATGTTC
AGCCTCGCCATTTATACCCAGTTGGCTGATCCGACTCTTCGTGATGGCCGCGATATTGCAGGGACCGGCAGCATCAGCCG
TGAAGGCGAAGTTGGCGAAATCGGCGGAATCGATAAGAAAGTCGTTTCAGCGGCCCAAAGCGGAGCAGACATCTTCTTTG
CACCGAACAATGAACTGACAGAGGAAGAGAAAAAGCTTTCTCCTAATGGGAAAAACAACTACCAAACGGCTCTGGAGACA
GCCAAGAAGATTAAAACGGATATGAAAATTGTTCCAGTTAAAACGCTGCAGGACGCCATTGACTATCTGAAAAAGAACAA
GTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-300)

• PDZ domain (PDZ_2) (128-195)

3D structure

• AlphaFold DB: A3CLL1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	58.092	99.712	0.579