Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   AM340_RS25770 Genome accession   NZ_CP032204
Coordinates   4985733..4987754 (-) Length   673 a.a.
NCBI ID   WP_000042532.1    Uniprot ID   B7NNK9
Organism   Escherichia coli strain AR_0013     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4980733..4992754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM340_RS25735 (AM340_26045) ybhL 4980846..4981550 (-) 705 WP_001361291.1 Bax inhibitor-1/YccA family protein -
  AM340_RS25740 (AM340_26050) moaE 4981687..4982139 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  AM340_RS25745 (AM340_26055) moaD 4982141..4982386 (-) 246 WP_000598605.1 molybdopterin synthase sulfur carrier subunit -
  AM340_RS25750 (AM340_26060) moaC 4982379..4982864 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  AM340_RS25755 (AM340_26065) moaB 4982867..4983379 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  AM340_RS25760 (AM340_26070) moaA 4983401..4984390 (-) 990 WP_001298683.1 GTP 3',8-cyclase MoaA -
  AM340_RS25765 (AM340_26075) yvcK 4984787..4985695 (+) 909 WP_001301716.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  AM340_RS25770 (AM340_26080) uvrB 4985733..4987754 (-) 2022 WP_000042532.1 excinuclease ABC subunit UvrB Machinery gene
  AM340_RS25775 (AM340_26085) bioD 4988333..4989010 (-) 678 WP_000044835.1 dethiobiotin synthase -
  AM340_RS25780 (AM340_26090) bioC 4989003..4989758 (-) 756 WP_000201219.1 malonyl-ACP O-methyltransferase BioC -
  AM340_RS25785 (AM340_26095) bioF 4989745..4990899 (-) 1155 WP_000118791.1 8-amino-7-oxononanoate synthase -
  AM340_RS25790 (AM340_26100) bioB 4990896..4991936 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76212.03 Da        Isoelectric Point: 4.8825

>NTDB_id=275065 AM340_RS25770 WP_000042532.1 4985733..4987754(-) (uvrB) [Escherichia coli strain AR_0013]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRDLFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=275065 AM340_RS25770 WP_000042532.1 4985733..4987754(-) (uvrB) [Escherichia coli strain AR_0013]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGTTGTATGGCGAAATGAAAGAATTC
TTCCCGGAAAACGCGGTGGAGTATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAGCAGATGCGTTTATCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTAGTGGCCTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGCGGTACTTTCCGCGTTCGTGGTGAGGTGATAGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCGGGGATTGAAAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTCCCTGCTGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGACCCGATTATCGAAGTGCGGCC
GGTGGCGACACAGGTTGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTGCTGGTCACCACAC
TGACCAAGCGAATGGCGGAAGATCTTACCGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAGCGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
TGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGTTGGGGCAGAACATTGCTAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGACCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAAATCCATGAGCTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
TTTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

Ultra-violet resistance protein B (UvrB)

(552-593)

UvrB/uvrC motif (UVR)

(634-667)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7NNK9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557

Multiple sequence alignment