Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   C5I45_RS04690 Genome accession   NZ_CP027061
Coordinates   899222..899866 (+) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus sp. ZY-1-1     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 894222..904866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5I45_RS04665 (C5I45_04660) - 894670..895011 (-) 342 WP_014305721.1 hypothetical protein -
  C5I45_RS04670 (C5I45_04665) degQ 895477..895617 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  C5I45_RS04675 (C5I45_04670) - 895825..896685 (+) 861 WP_159073777.1 polyprenyl synthetase family protein -
  C5I45_RS04680 (C5I45_04675) comX 896654..896827 (+) 174 WP_012118314.1 competence pheromone ComX -
  C5I45_RS04685 (C5I45_04680) comP 896841..899141 (+) 2301 WP_107994251.1 histidine kinase Regulator
  C5I45_RS04690 (C5I45_04685) comA 899222..899866 (+) 645 WP_003152052.1 response regulator transcription factor Regulator
  C5I45_RS04695 (C5I45_04690) - 899888..900271 (+) 384 WP_003152054.1 hotdog fold thioesterase -
  C5I45_RS04700 (C5I45_04695) mnhG 900311..900685 (-) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  C5I45_RS04705 (C5I45_04700) - 900669..900953 (-) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  C5I45_RS04710 (C5I45_04705) - 900953..901429 (-) 477 WP_003152059.1 Na+/H+ antiporter subunit E -
  C5I45_RS04715 (C5I45_04710) - 901435..902916 (-) 1482 WP_014305717.1 Na+/H+ antiporter subunit D -
  C5I45_RS04720 (C5I45_04715) - 902909..903250 (-) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  C5I45_RS04725 (C5I45_04720) - 903250..903681 (-) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=274793 C5I45_RS04690 WP_003152052.1 899222..899866(+) (comA) [Bacillus sp. ZY-1-1]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=274793 C5I45_RS04690 WP_003152052.1 899222..899866(+) (comA) [Bacillus sp. ZY-1-1]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment