Detailed information NTG0027461

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: LLMG_RS04640
• Genome accession: NC_009004
• Coordinates: 874968..876440 (+)
• Length: 490 a.a.
• NCBI ID: WP_041931273.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris MG1363
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 869968..881440

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLMG_RS04610 (llmg_0903)	-	870444..871280 (+)	837	WP_011834858.1	metallophosphoesterase	-
LLMG_RS04615 (llmg_0904)	-	871373..872284 (+)	912	WP_011676635.1	CHAP domain-containing protein	-
LLMG_RS04620 (llmg_0905)	-	872521..872883 (+)	363	WP_011834859.1	TIGR02328 family protein	-
LLMG_RS04625 (llmg_0906)	-	873207..873452 (+)	246	WP_011676633.1	type B 50S ribosomal protein L31	-
LLMG_RS04630 (llmg_0907)	-	873585..874115 (+)	531	WP_011834860.1	YceD family protein	-
LLMG_RS04635 (llmg_0908)	covR	874271..874963 (+)	693	WP_011834861.1	response regulator transcription factor	Regulator
LLMG_RS04640 (llmg_0909)	covS	874968..876440 (+)	1473	WP_041931273.1	HAMP domain-containing sensor histidine kinase	Regulator
LLMG_RS04645 (llmg_0910)	-	876626..877867 (+)	1242	WP_011834863.1	ammonium transporter	-
LLMG_RS04650 (llmg_0911)	-	877949..878290 (+)	342	WP_011676628.1	P-II family nitrogen regulator	-
LLMG_RS04655 (llmg_0912)	murD	878459..879808 (+)	1350	WP_011834864.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-
LLMG_RS04660 (llmg_0913)	murG	880051..881124 (+)	1074	WP_011676626.1	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	-

Sequence

Protein

• Length: 490 a.a.
• Molecular weight: 55862.69 Da
• Isoelectric Point: 4.7011

>NTDB_id=27461 LLMG_RS04640 WP_041931273.1 874968..876440(+) (covS) [Lactococcus cremoris subsp. cremoris MG1363]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSAEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide

• Length: 1473 bp

>NTDB_id=27461 LLMG_RS04640 WP_041931273.1 874968..876440(+) (covS) [Lactococcus cremoris subsp. cremoris MG1363]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGCTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGATCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTAGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGTAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTGCTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (267-332)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (380-488)

• ArlS sensor domain (ArlS_N) (54-185)

• HAMP domain (HAMP) (208-258)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	94.49	100	0.945