Detailed information NTG0274231

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: D2E16_RS11965
• Genome accession: NZ_CP032064
• Coordinates: 2458825..2461365 (-)
• Length: 846 a.a.
• NCBI ID: WP_192369086.1
• Uniprot ID: -
• Organism: Streptococcus suis strain YSJ17
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2453825..2466365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D2E16_RS11935 (D2E16_12320)	-	2454214..2454840 (-)	627	WP_044687963.1	nitroreductase family protein	-
D2E16_RS11940 (D2E16_12325)	-	2454856..2456199 (-)	1344	WP_044687962.1	dihydrolipoyl dehydrogenase family protein	-
D2E16_RS11945 (D2E16_12330)	-	2456211..2456891 (-)	681	WP_024418369.1	type 1 glutamine amidotransferase domain-containing protein	-
D2E16_RS11950 (D2E16_12335)	-	2457024..2457461 (+)	438	WP_024418370.1	MarR family winged helix-turn-helix transcriptional regulator	-
D2E16_RS11955 (D2E16_12340)	-	2457590..2457991 (-)	402	WP_105131348.1	hypothetical protein	-
D2E16_RS11960 (D2E16_12345)	-	2458006..2458554 (-)	549	WP_225620753.1	hypothetical protein	-
D2E16_RS11965 (D2E16_12350)	hexA	2458825..2461365 (-)	2541	WP_192369086.1	DNA mismatch repair protein MutS	Machinery gene
D2E16_RS11970 (D2E16_12355)	argR	2461380..2461820 (-)	441	WP_044671978.1	arginine repressor	-
D2E16_RS11975 (D2E16_12360)	argS	2461927..2463615 (+)	1689	WP_053863622.1	arginine--tRNA ligase	-
D2E16_RS12595	-	2463919..2465676 (+)	1758	WP_225620754.1	SH3 domain-containing protein	-
D2E16_RS11995 (D2E16_12380)	-	2465726..2466250 (-)	525	WP_002941931.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95138.57 Da
• Isoelectric Point: 4.7721

>NTDB_id=274231 D2E16_RS11965 WP_192369086.1 2458825..2461365(-) (hexA) [Streptococcus suis strain YSJ17]
MATEKISPGMQQYLDIKANYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNYLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNVPAIKNILLQMDQSALTSLVAGLDPIPELHALISSAIDP
EAQGAITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSSNLEYEIFMRIRQEVEKYISRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLERADRILQTLENQAPTAPANPAPSVV
EEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=274231 D2E16_RS11965 WP_192369086.1 2458825..2461365(-) (hexA) [Streptococcus suis strain YSJ17]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCAAACTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GCAACAAAAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCATATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
ACAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACAGAGGATGTCCAATTGATTGATAACTACTTGACAG
ATTTGGAAAAGGCTGCGGCGGGCAAACTCCTCAGCTACCTGCACCGGACACAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACTTACTTGAAAATGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTGGATGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAACTTTCTCAGACCCTTGGAAATGTCCCTGCTATCAAGAATATCTTGCTACAAATGGATC
AGTCTGCTCTGACTAGCTTGGTGGCAGGTCTGGATCCAATCCCAGAACTACACGCCCTTATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGGCTATTACAGATGGAAATATCATCCGTACGGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTCAT
GCGTGAGGGGGCGGGCTGGATTGCGGAGATTGAGGCCAAAGAGCGTGAAGCGTCTGGTATCAACAATCTCAAGATTGATT
ACAACAAAAAAGACGGTTACTACTTCCATGTGACCAATTCTAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGTACGGAAGAATTGGCTAAGATTGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
GTCTAACTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAAAAATACATCAGCCGTTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTCTTGCAGGCTTTTGCGGTTGTGGCGGAGCAACAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGATCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACCTGAATACCGATACGCATATGCAACTAATTACAGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGAC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAGATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCTCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCCAAGACCCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCAGGAATGCCAGAGGAGTTAT
TGGAGCGAGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAGCTAACCCAGCTCCGTCAGTAGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCGATGGAAGTCATGATGGCTGTGGCGGAGTTAAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.995	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	37.398	100	0.381