Detailed information NTG0274074

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK60_RS13675
• Genome accession: NZ_CP026968
• Coordinates: 2579157..2580044 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain FDAARGOS_1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2574157..2585044

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK60_RS13640 (RK60_13640)	-	2574176..2574268 (+)	93	WP_010956583.1	hypothetical protein	-
RK60_RS13645 (RK60_13645)	-	2574376..2574873 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK60_RS13650 (RK60_13650)	-	2574883..2575143 (-)	261	WP_001791974.1	hypothetical protein	-
RK60_RS13660 (RK60_13660)	-	2575525..2575638 (-)	114	Protein_2546	hypothetical protein	-
RK60_RS13665 (RK60_13665)	-	2576297..2578297 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK60_RS13670 (RK60_13670)	-	2578294..2579049 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK60_RS13675 (RK60_13675)	braS	2579157..2580044 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK60_RS13680 (RK60_13680)	braR	2580055..2580720 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK60_RS13685 (RK60_13685)	-	2580746..2580946 (-)	201	WP_000604730.1	hypothetical protein	-
RK60_RS13690 (RK60_13690)	-	2581144..2582568 (+)	1425	WP_000953755.1	alkaline phosphatase	-
RK60_RS15285 (RK60_13695)	-	2582628..2582729 (-)	102	WP_000731976.1	SE2200 family small protein	-
RK60_RS13700 (RK60_13700)	-	2582851..2583306 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK60_RS13705 (RK60_13705)	-	2583551..2584312 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=274074 RK60_RS13675 WP_000143425.1 2579157..2580044(-) (braS) [Staphylococcus aureus strain FDAARGOS_1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=274074 RK60_RS13675 WP_000143425.1 2579157..2580044(-) (braS) [Staphylococcus aureus strain FDAARGOS_1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1