Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RK64_RS10785 Genome accession   NZ_CP026962
Coordinates   2114110..2114835 (+) Length   241 a.a.
NCBI ID   WP_000688494.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2109110..2119835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK64_RS10755 (RK64_10755) - 2109329..2109955 (+) 627 WP_000522384.1 nitroreductase family protein -
  RK64_RS10760 (RK64_10760) - 2110316..2111101 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  RK64_RS14475 hld 2111698..2111778 (-) 81 WP_000046022.1 delta-hemolysin -
  RK64_RS10770 (RK64_10770) agrB 2112068..2112637 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  RK64_RS10775 (RK64_10775) agrD 2112634..2112774 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  RK64_RS10780 (RK64_10780) agrC 2112799..2114091 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  RK64_RS10785 (RK64_10785) agrA 2114110..2114835 (+) 726 WP_000688494.1 quorum-sensing response regulator AgrA Regulator
  RK64_RS10790 (RK64_10790) - 2114899..2115006 (+) 108 WP_001790167.1 hypothetical protein -
  RK64_RS10795 (RK64_10795) - 2115194..2116153 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  RK64_RS10800 (RK64_10800) - 2116150..2117634 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  RK64_RS10805 (RK64_10805) - 2117783..2118733 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 28289.35 Da        Isoelectric Point: 6.3009

>NTDB_id=273986 RK64_RS10785 WP_000688494.1 2114110..2114835(+) (agrA) [Staphylococcus aureus strain FDAARGOS_6]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKNII
R

Nucleotide


Download         Length: 726 bp        

>NTDB_id=273986 RK64_RS10785 WP_000688494.1 2114110..2114835(+) (agrA) [Staphylococcus aureus strain FDAARGOS_6]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAATATAATA
AGATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

98.34

0.983

Multiple sequence alignment