Detailed information NTG0273915

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RK68_RS04455
• Genome accession: NZ_CP026961
• Coordinates: 777752..778639 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_10
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 772752..783639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK68_RS04420 (RK68_04420)	-	772771..772863 (+)	93	WP_010956583.1	hypothetical protein	-
RK68_RS04425 (RK68_04425)	-	772971..773468 (-)	498	WP_001065268.1	glutathione peroxidase	-
RK68_RS04430 (RK68_04430)	-	773478..773738 (-)	261	WP_001789910.1	hypothetical protein	-
RK68_RS04440 (RK68_04440)	-	774120..774233 (-)	114	WP_011447078.1	hypothetical protein	-
RK68_RS04445 (RK68_04445)	-	774892..776892 (-)	2001	WP_000776751.1	ABC transporter permease	-
RK68_RS04450 (RK68_04450)	-	776889..777644 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RK68_RS04455 (RK68_04455)	braS	777752..778639 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RK68_RS04460 (RK68_04460)	braR	778650..779315 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RK68_RS04465 (RK68_04465)	-	779341..779541 (-)	201	WP_000604728.1	hypothetical protein	-
RK68_RS04470 (RK68_04470)	-	779739..781163 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RK68_RS15520 (RK68_04475)	-	781223..781324 (-)	102	WP_000731972.1	SE2200 family small protein	-
RK68_RS04480 (RK68_04480)	-	781446..781901 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RK68_RS04485 (RK68_04485)	-	782146..782907 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=273915 RK68_RS04455 WP_000143419.1 777752..778639(-) (braS) [Staphylococcus aureus strain FDAARGOS_10]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=273915 RK68_RS04455 WP_000143419.1 777752..778639(-) (braS) [Staphylococcus aureus strain FDAARGOS_10]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997